SCHEMBL5810491

SCHEMBL5810491

CC1=C(O)C(=O)c2c(O)ccc(O)c2C1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.52
KMT2A Q03164 8/20 0.52
MAPT P10636 7/20 0.52
KDM4E B2RXH2 5/20 0.52
RECQL P46063 5/20 0.52
ALDH1A1 P00352 5/20 0.52
MAPK1 P28482 5/20 0.52
USP2 O75604 4/20 0.52
BLM P54132 4/20 0.52
THRB P10828 2/20 0.52
TXNRD1 Q16881 2/20 0.52
POLB P06746 2/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
GAA P10253 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
MAOA P21397 4/20 0.48
HPGD P15428 6/20 0.47
CSNK2A2 P19784 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30004289 1.00 MEN1 (0.52) MEN1KMT2AMAPTKDM4ERECQL
SCHEMBL198006 0.87 MAPT (0.58) MEN1KMT2AMAPTKDM4ERECQL
SCHEMBL30002568 0.87 MAPT (0.58) MEN1KMT2AMAPTKDM4ERECQL
SCHEMBL5818577 0.82 MEN1 (0.59) MEN1KMT2AMAPTKDM4ERECQL
SCHEMBL23271652 0.79 MAPT (0.60) MEN1KMT2AMAPTKDM4ERECQL
SCHEMBL30002528 0.79 MAPT (0.60) MEN1KMT2AMAPTKDM4ERECQL
SCHEMBL5821552 0.79 MAPT (0.60) MEN1KMT2AMAPTKDM4ERECQL
SCHEMBL17183612 0.77 MEN1 (0.48) MEN1KMT2AMAPTKDM4ERECQL
SCHEMBL5817676 0.77 MAOA (0.67) MEN1KMT2AMAPTKDM4ERECQL
Droserone SCHEMBL5858407 0.77 MAOA (0.67) MEN1KMT2AMAPTKDM4ERECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006107827-A1 SKIN BONDING PROCESS CREIGHTON UNIVERSITY (US) 2006-10-12 WO claimed
US-11613509-B2 Radical polymerization control agent and radical polymerization control method KAWASAKI KASEI CHEMICALS LTD. (JP) 2023-03-28 US disclosed
CN-110891980-B Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2022-09-30 CN disclosed
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD KAWASAKI KASEI CHEMICALS LTD. (JP) 2021-04-29 US disclosed
CN-110891980-A Radical polymerization control agent and radical polymerization control method 川崎化成工业株式会社 2020-03-17 CN disclosed
WO-2006107827-A1 SKIN BONDING PROCESS CREIGHTON UNIVERSITY (US) 2006-10-12 WO disclosed
US-4933399-A COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613509-B2 Radical polymerization control agent and radical polymerization control method PPOX, NOX4, CROCC MEN1 2943/4885KMT2A 2246/4885MAPT 188/4885
US-20210122692-A1 RADICAL POLYMERIZATION CONTROL AGENT AND RADICAL POLYMERIZATION CONTROL METHOD PPOX, NOX4, CROCC MEN1 2943/4885KMT2A 2246/4885MAPT 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.