Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428995 | 0.89 | RYR2 (0.83) | RYR2 | |
| SCHEMBL3426026 | 0.81 | RYR2 (0.58) | RYR2 | |
| SCHEMBL3425724 | 0.81 | RYR2 (0.80) | RYR2 | |
| Aladorian SCHEMBL3423110 | 0.80 | RYR2 (1.00) | RYR2 | |
| Aladorian SCHEMBL29379838 | 0.80 | RYR2 (1.00) | RYR2 | |
| SCHEMBL29134507 | 0.79 | RYR2 (0.51) | RYR2 | |
| SCHEMBL807117 | 0.78 | RYR2 (0.79) | RYR2 | |
| SCHEMBL3428542 | 0.77 | RYR2 (0.77) | RYR2 | |
| SCHEMBL806687 | 0.77 | RYR2 (1.00) | RYR2 | |
| SCHEMBL11295872 | 0.77 | ESR1 (0.71) | RYR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250159-A1 | PROCESS FOR PREPARING BENZOTHIAZEPINES FROM GAMMA-AMINOALKYLBENZENES | Armgo Pharma, Inc. (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009111463-A1 | PROCESS FOR PREPARING BENZOTHIAZEPINES FROM GAMMA-AMINOALKYLBENZENES | ARMGO PHARMA, INC. (US) | 2009-09-11 | — | — | WO | disclosed |