SCHEMBL342905

SCHEMBL342905

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nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.62
LMNA P02545 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.55
TDP1 Q9NUW8 2/20 0.52
USP2 O75604 1/20 0.46
SLCO1B1 Q9Y6L6 1/20 0.46
KDM4E B2RXH2 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.34
TOP1 P11387 1/20 0.32
OR51E2 Q9H255 1/20 0.31
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30854320 1.00 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL671091 1.00 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL30854304 1.00 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL17931825 1.00 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL9961490 1.00 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL16968414 1.00 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL16491025 1.00 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL27398 1.00 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL13998184 1.00 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2
SCHEMBL30854383 1.00 PDE4A (0.62) PDE4ALMNAL3MBTL1TDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 358 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240301178-A1 POLYSACCHARIDE COMPLEX ACARYON GMBH (DE) 2024-09-12 US claimed
CN-117903386-A Method for realizing liquid phase polymerization of high-concentration polyhydroxy aldehyde or (and) polyhydroxy ketone through liquid thereof under high-temperature condition 厦门碳控科技投资有限公司 2024-04-19 CN claimed
EP-4294447-A1 POLYSACCHARIDE COMPLEX Acaryon GmbH (DE) 2023-12-27 EP claimed
CN-117157100-A Polysaccharide complexes 阿卡扬股份有限公司 2023-12-01 CN claimed
WO-2023091441-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2023-05-25 WO claimed
WO-2022175390-A1 POLYSACCHARIDE COMPLEX ACARYON GMBH (DE) 2022-08-25 WO claimed
EP-3740212-A2 CONJUGATE BASED SYSTEMS FOR CONTROLLED INSULIN DELIVERY Merck Sharp & Dohme Corp. (US) 2020-11-25 EP claimed
EP-2391218-B1 CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY SMARTCELLS INC (US) 2020-03-18 EP claimed
EP-3280450-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES Merck Sharp & Dohme Corp. (US) 2018-02-14 EP claimed
WO-2016164288-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES MERCK SHARP & DOHME CORP. (US) 2016-10-13 WO claimed
US-20110281792-A1 BINDING-SITE MODIFIED LECTINS AND USES THEREOF SMARTCELLS, INC. 2011-11-17 US claimed
US-20110281939-A1 POLYNUCLEOTIDE APTAMER-BASED CROSS-LINKED MATERIALS AND USES THEREOF SMARTCELLS, INC. 2011-11-17 US claimed
US-20110275560-A1 SYNTHETIC CONJUGATES AND USES THEREOF SMARTCELLS, INC. 2011-11-10 US claimed
WO-2010107520-A1 SOLUBLE NON-DEPOT INSULIN CONJUGATES AND USES THEREOF SMARTCELLS, INC. (US) 2010-09-23 WO claimed
WO-2010107519-A1 TERMINALLY-FUNCTIONALIZED CONJUGATES AND USES THEREOF SMARTCELLS, INC. (US) 2010-09-23 WO claimed
WO-2010088286-A1 SYNTHETIC CONJUGATES AND USES THEREOF SMARTCELLS, INC. (US) 2010-08-05 WO claimed
WO-2010088276-A2 POLYNUCLEOTIDE APTAMER-BASED CROSS -LINKED MATERIALS AND USES THEREOF SMARTCELLS, INC. (US) 2010-08-05 WO claimed
WO-2010088261-A1 BINDING-SITE MODIFIED LECTINS AND USES THEREOF SMARTCELLS, INC. (US) 2010-08-05 WO claimed
WO-2010088294-A1 CONJUGATE BASED SYSTEMS FOR CONTROLLED DRUG DELIVERY SMARTCELLS, INC. (US) 2010-08-05 WO claimed
WO-2010088268-A1 EXOGENOUSLY TRIGGERED CONTROLLED RELEASE MATERIALS AND USES THEREOF SMARTCELLS, INC. (US) 2010-08-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275560-A1 SYNTHETIC CONJUGATES AND USES THEREOF SLC2A4, SLC2A8, CD44 PDE4A 4326/4885LMNA 4457/4885L3MBTL1 1047/4885
US-20240301178-A1 POLYSACCHARIDE COMPLEX SGMS1, UGCG, SGMS2 PDE4A 2432/4885LMNA 1448/4885L3MBTL1 3218/4885
US-20110281792-A1 BINDING-SITE MODIFIED LECTINS AND USES THEREOF SIGLEC7, SIGLEC9, LGALS3BP PDE4A 3569/4885LMNA 1669/4885L3MBTL1 295/4885
US-20110281939-A1 POLYNUCLEOTIDE APTAMER-BASED CROSS-LINKED MATERIALS AND USES THEREOF PNKP, ADAR, NCL PDE4A 1267/4885LMNA 934/4885L3MBTL1 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.