Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.56 |
| ▸ | AGT | P01019 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498022 | 0.94 | AGTR2 (0.63) | AGTR1AGTR2AGT | |
| SCHEMBL2924610 | 0.89 | AGTR2 (0.55) | AGTR1AGTR2AGT | |
| SCHEMBL14855137 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2AGT | |
| SCHEMBL809 | 0.86 | AGT (0.57) | AGTR1AGTR2AGT | |
| SCHEMBL7310565 | 0.85 | AGTR1 (0.59) | AGTR1AGTR2AGT | |
| SCHEMBL3425230 | 0.85 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9313215 | 0.85 | AGTR2 (0.56) | AGTR1AGTR2AGT | |
| SCHEMBL7312342 | 0.85 | AGTR1 (0.58) | AGTR1AGTR2AGT | |
| SCHEMBL9271493 | 0.84 | AGT (0.48) | AGTR1AGTR2AGT | |
| SCHEMBL7310270 | 0.83 | AGTR1 (0.57) | AGTR1AGTR2AGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250158-A2 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | Nicox S.A. (FR) | 2010-11-17 | — | — | EP | disclosed |
| EP-2244575-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009106470-A2 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | NICOX S.A. (FR) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009094242-A1 | ANGIOTENSIN II RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2009-07-30 | — | — | WO | disclosed |
| US-5254574-A | Angiotensin II inhibitor | CHEMISCH PHARMAZEUTISCHE FORSCHUNGSGESELLSCHAFT M.B.H. (AT) | 1993-10-19 | — | — | US | disclosed |