Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 known ✓ | P0DMS8 | 4/20 | 0.66 |
| ▸ | ADORA1 known ✓ | P30542 | 2/20 | 0.66 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.66 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.66 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.66 |
| ▸ | DPP4 | P27487 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.66 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.66 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.66 |
| ▸ | GAPDH | P04406 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | STAT6 | P42226 | 1/20 | 0.66 |
| ▸ | PI4KA | P42356 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.66 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.66 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.66 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL16319999 | 0.93 | ADORA3 (0.56) | ADORA3DOT1LADORA1DPP4MEN1 | |
| Adenosine SCHEMBL15753116 | 0.93 | ADORA3 (0.56) | ADORA3DOT1LADORA1DPP4MEN1 | |
| Inosine SCHEMBL28379793 | 0.92 | ADORA3 (0.55) | ADORA3DOT1LADORA1DPP4MEN1 | |
| Adenosine SCHEMBL5226826 | 0.92 | ADORA3 (0.56) | ADORA3DOT1LADORA1DPP4MEN1 | |
| Adenosine SCHEMBL27813101 | 0.91 | ADORA3 (0.74) | ADORA3DOT1LADORA1DPP4MEN1 | |
| Adenosine SCHEMBL21854749 | 0.91 | ADORA3 (0.54) | ADORA3DOT1LADORA1DPP4MEN1 | |
| Adenosine SCHEMBL9736217 | 0.90 | ADORA3 (0.59) | ADORA3DOT1LADORA1DPP4MEN1 | |
| Guanosine SCHEMBL8995759 | 0.90 | HPGD (0.62) | ADORA3ADORA2AHPGD | |
| Adenosine SCHEMBL28574438 | 0.90 | ADORA3 (0.61) | ADORA3DOT1LADORA1DPP4MEN1 | |
| Guanosine SCHEMBL29045171 | 0.88 | HPGD (0.60) | ADORA3ADORA2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023176708-A1 | CLEANING COMPOSITION AND SEMICONDUCTOR SUBSTRATE CLEANING METHOD | 富士フイルム株式会社 | 2023-09-21 | — | — | WO | disclosed |
| CN-114636761-A | Method for detecting adsorption efficiency of drug to nucleic acid metabolites and application thereof | 中美华世通生物医药科技(武汉)股份有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-7741033-B2 | Using nanowire immobilized probes to generate profiles for rapid and inexpensive detection and identification of bacterial pathogens; genomic analysis | TRUSTEES OF BOSTON COLLEGE (US) | 2010-06-22 | — | — | US | disclosed |
| EP-1629122-B1 | ELECTROCATALYTIC NUCLEIC ACID HYBRIDIZATION DETECTION | TRUSTEES BOSTON COLLEGE (US) | 2009-10-14 | — | — | EP | disclosed |
| US-20090017047-A1 | Preparation for the Prevention and Treatment of Stress Conditions as Well as Functional and Organic Disorders of the Nervous System and Metabolic Disorders | TECH EGON | 2009-01-15 | — | — | US | disclosed |
| US-7361470-B2 | Electrocatalytic nucleic acid hybridization detection | TRUSTEES OF BOSTON COLLEGE (US) | 2008-04-22 | — | — | US | disclosed |
| US-20080014634-A1 | Selective cloning of homoduplex nucleic acids | GREENER ALAN L | 2008-01-17 | — | — | US | disclosed |
| EP-1629122-A4 | ELECTROCATALYTIC NUCLEIC ACID HYBRIDIZATION DETECTION | TRUSTEES BOSTON COLLEGE (US) | 2007-12-26 | — | — | EP | disclosed |
| EP-1784512-A2 | ELECTROCATALYTIC NUCLEIC ACID HYBRIDIZATION DETECTION | The Trustees of Boston College (US) | 2007-05-16 | — | — | EP | disclosed |
| US-7148339-B2 | Temperature sensitive mutant of bacteriophage T4 endonuclease VII | STRATAGENE CALIFORNIA (US) | 2006-12-12 | — | — | US | disclosed |
| US-20060223079-A1 | Electrocatalytic nucleic acid hybridization detection | TRUSTEES OF BOSTON COLLEGE | 2006-10-05 | — | — | US | disclosed |
| WO-2006076047-A2 | ELECTROCATALYTIC NUCLEIC ACID HYBRIDIZATION DETECTION | THE TRUSTEES OF BOSTON COLLEGE (US) | 2006-07-20 | — | — | WO | disclosed |
| EP-1629122-A2 | ELECTROCATALYTIC NUCLEIC ACID HYBRIDIZATION DETECTION | The Trustees of Boston College (US) | 2006-03-01 | — | — | EP | disclosed |
| US-20050186676-A1 | Selective cloning of homoduplex nucleic acids | GREENER ALAN L (US) | 2005-08-25 | — | — | US | disclosed |
| US-20050084881-A1 | Using nanowire immobilized probes to generate profiles for rapid and inexpensive detection and identification of bacterial pathogens; genomic analysis | TRUSTEES OF BOSTON COLLEGE | 2005-04-21 | — | — | US | disclosed |
| WO-2005005952-A2 | ELECTROCATALYTIC NUCLEIC ACID HYBRIDIZATION DETECTION | THE TRUSTEES OF BOSTON COLLEGE (US) | 2005-01-20 | — | — | WO | disclosed |
| WO-2004003135-A2 | SELECTIVE CLONING OF HOMODUPLEX NUCLEIC ACIDS | STRATAGENE (US) | 2004-01-08 | — | — | WO | disclosed |
| US-20040002155-A1 | Endonuclease VII cloning method | STRATAGENE | 2004-01-01 | — | — | US | disclosed |
| US-20040002156-A1 | Selective cloning of homoduplex nucleic acids | STRATAGENE | 2004-01-01 | — | — | US | disclosed |