Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12358988 | 0.91 | POLB (0.38) | POLBACHENPSR1NPC1RAB9A | |
| SCHEMBL342076 | 0.78 | NPSR1 (0.41) | NPSR1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL338481 | 0.73 | NPSR1 (0.47) | NPSR1SMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL12359000 | 0.72 | KMT2A (0.36) | POLBACHENPSR1KMT2AALDH1A1 | |
| SCHEMBL12373146 | 0.72 | NPSR1 (0.39) | NPSR1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL12359001 | 0.72 | POLB (0.35) | POLBACHENPSR1KMT2AALDH1A1 | |
| SCHEMBL5546530 | 0.71 | ALDH1A1 (0.45) | POLBACHENPSR1NPC1RAB9A | |
| SCHEMBL348276 | 0.70 | NPSR1 (0.42) | POLBNPSR1KMT2AALDH1A1LMNA | |
| SCHEMBL338765 | 0.69 | NPSR1 (0.41) | NPSR1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL12306124 | 0.69 | NPSR1 (0.41) | NPSR1NPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321319-B1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES INC (US) | 2012-03-14 | — | — | EP | disclosed |