⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431181 | 0.94 | — | — | |
| SCHEMBL1710537 | 0.91 | — | — | |
| SCHEMBL3964484 | 0.87 | — | — | |
| SCHEMBL3020072 | 0.69 | — | — | |
| Cyclobutane Carbaldehyde SCHEMBL29132323 | 0.69 | ADH1C (0.31) | — | |
| SCHEMBL19614685 | 0.65 | TDP1 (0.35) | — | |
| SCHEMBL24925882 | 0.63 | — | — | |
| SCHEMBL3622546 | 0.63 | — | — | |
| SCHEMBL4495154 | 0.63 | TDP1 (0.33) | — | |
| SCHEMBL9918775 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7354936-B2 | 2-phenylpyran-4-one derivatives | ALMIRALL AG (CH) | 2008-04-08 | — | — | US | claimed |
| EP-1263751-B1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2004-06-16 | — | — | EP | claimed |
| US-20030232880-A1 | 2-Phenylpyran-4-one derivatives | LABORATORIOS ALMIRALL, S.A. (ES) | 2003-12-18 | — | — | US | claimed |
| CN-111303147-B | Pyridone derivatives, compositions thereof and use as anti-influenza virus medicaments | 江西彩石医药科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117534725-A | Linker, linker-drug conjugate, ligand-drug conjugate and uses thereof | 北京海步医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-117500528-A | Linker and conjugate thereof | 北京海步医药科技有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117247380-A | Thiazole derivative, and pharmaceutical composition and application thereof | 苏州远智医药科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117229223-A | Heterocyclic derivative, and pharmaceutical composition and application thereof | 苏州远智医药科技有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023236752-A1 | HETEROCYCLIC DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 苏州远智医药科技有限公司 | 2023-12-14 | — | — | WO | disclosed |
| CN-112592343-B | Polycyclic compound and application thereof as antiviral drug | 周雨恬 | 2023-05-16 | — | — | CN | disclosed |
| CN-115677703-A | Pyridone compound and use thereof | 苏州远智医药科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-110637016-A | Pyridone derivative, composition thereof and application of pyridone derivative as anti-influenza virus medicament | 银杏树药业(苏州)有限公司 | 2019-12-31 | — | — | CN | disclosed |
| WO-2019141179-A1 | PYRIDONE DERIVATIVE, COMPOSITION THEREOF AND APPLICATION THEREOF AS ANTI-INFLUENZA DRUG | 银杏树药业(苏州)有限公司 | 2019-07-25 | — | — | WO | disclosed |
| EP-3492467-A1 | ISOQUINOLINONE COMPOUND AND USE THEREOF IN PREPARATION OF ANTIVIRAL DRUGS | Ginkgo Pharma Co., Ltd. (CN) | 2019-06-05 | — | — | EP | disclosed |
| US-7691867-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2010-04-06 | — | — | US | disclosed |
| CN-101374844-A | Pyrrolopyridazinone compound | UBE INDUSTRIES (JP) | 2009-02-25 | — | — | CN | disclosed |
| EP-1613619-B1 | QUINAZOLINE DERIVATIVES FOR TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-03-26 | — | — | EP | disclosed |
| US-20060270692-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | US | disclosed |
| EP-1613619-A1 | QUINAZOLINE DERIVATIVES FOR TREATMENT OF CANCER | AstraZeneca AB (SE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004094410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-11-04 | — | — | WO | disclosed |