Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 19/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.51 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | PTGIR | P43119 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15021299 | 0.93 | PTGDR2 (0.46) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL17387610 | 0.91 | PTGDR2 (0.56) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL153736 | 0.83 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3432155 | 0.81 | PTGDR2 (0.57) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3433110 | 0.81 | PTGDR2 (0.65) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL140978 | 0.80 | PTGDR2 (0.78) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3430242 | 0.80 | RXRA (0.40) | PTGDR2RXRARXRBRXRG | |
| SCHEMBL3432794 | 0.79 | PTGDR2 (0.65) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL3425530 | 0.79 | PTGDR2 (0.57) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL17387633 | 0.78 | PTGDR2 (0.65) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257524-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009099902-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |