Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459575 | 0.95 | — | — | |
| SCHEMBL9483038 | 0.93 | MEN1 (0.40) | MEN1POLBKMT2ACA1CA2 | |
| SCHEMBL1005540 | 0.93 | MEN1 (0.40) | MEN1POLBKMT2ACA1CA2 | |
| SCHEMBL3679043 | 0.93 | MEN1 (0.40) | MEN1POLBKMT2ACA1CA2 | |
| SCHEMBL9484160 | 0.93 | MEN1 (0.40) | MEN1POLBKMT2ACA1CA2 | |
| SCHEMBL9483893 | 0.93 | MEN1 (0.40) | MEN1POLBKMT2ACA1CA2 | |
| SCHEMBL28632214 | 0.93 | MEN1 (0.40) | MEN1POLBKMT2ACA1CA2 | |
| SCHEMBL923937 | 0.93 | MEN1 (0.40) | MEN1POLBKMT2ACA1CA2 | |
| SCHEMBL28269242 | 0.91 | MEN1 (0.39) | MEN1POLBKMT2ACA1CA2 | |
| SCHEMBL926527 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035800-A1 | NOVEL FORMULATIONS OF PHARMACOLOGICAL AGENTS, METHODS FOR THE PREPARATION THEREOF AND METHODS FOR THE USE THEREOF | AMERICAN BIOSCIENCE, INC. | 2010-02-11 | — | — | US | disclosed |
| US-20080213370-A1 | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof | ABRAXIS BIOSCIENCE, INC. | 2008-09-04 | — | — | US | disclosed |
| US-20070128290-A1 | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof | ABRAXIS BIOSCIENCE, INC. (US) | 2007-06-07 | — | — | US | disclosed |