SCHEMBL459575

SCHEMBL459575

[CH2]CCCCOCC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9484160 0.97 MEN1 (0.40)
SCHEMBL9483038 0.97 MEN1 (0.40)
SCHEMBL1005540 0.97 MEN1 (0.40)
SCHEMBL3679043 0.97 MEN1 (0.40)
SCHEMBL9483893 0.97 MEN1 (0.40)
SCHEMBL28632214 0.97 MEN1 (0.40)
SCHEMBL923937 0.97 MEN1 (0.40)
SCHEMBL3430285 0.95 MEN1 (0.39)
SCHEMBL28269242 0.95 MEN1 (0.39)
SCHEMBL926527 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024110998-A1 A STEROGENIC 3,3-DISUBSTITUTED 3-AMINO OXINDOLE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-05-30 WO claimed
US-20080161232-A1 C5a is a cleavage product of the complement cascade, the CS convertase; antiinflammatory agents; autoimmune diseases; cyclic peptide compounds JERINI AG (DE) 2008-07-03 US claimed
EP-1838725-A1 C5A RECEPTOR ANTAGONISTS Jerini AG (DE) 2007-10-03 EP claimed
US-20070155712-A1 Compounds for the inhibition of angiogenesis and use thereof JERINI AG (DE) 2007-07-05 US claimed
WO-2005090329-A9 NEW COMPOUNDS FOR THE INHIBITION OF ANGIOGENESIS AND USE OF THEREOF JERINI AG (DE) 2007-02-01 WO claimed
EP-1727811-A1 NEW COMPOUNDS FOR THE INHIBITION OF ANGIOGENESIS AND USE OF THEREOF Jerini AG (DE) 2006-12-06 EP claimed
US-20060183883-A1 C5a Receptor antagonists JERINI AG (DE) 2006-08-17 US claimed
WO-2006074964-A1 C5A RECEPTOR ANTAGONISTS JERINI AG (DE) 2006-07-20 WO claimed
WO-2005090329-A1 NEW COMPOUNDS FOR THE INHIBITION OF ANGIOGENESIS AND USE OF THEREOF JERINI AG (DE) 2005-09-29 WO claimed
EP-1438310-A1 BETA-CARBOLIN DERIVATIVES AS PTP-INHIBITORS TransTech Pharma Inc. (US) 2004-07-21 EP claimed
WO-2003033496-A1 BETA-CARBOLIN DERIVATIVES AS PTP-INHIBITORS TRANSTECH PHARMA, INC. (US) 2003-04-24 WO claimed
WO-2024110998-A1 A STEROGENIC 3,3-DISUBSTITUTED 3-AMINO OXINDOLE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-05-30 WO disclosed
WO-2023235925-A1 COMPOUNDS WITH MERTK ACTIVITY MONASH UNIVERSITY (AU) 2023-12-14 WO disclosed
CN-117121184-A Optical semiconductor device, method for manufacturing the same, solid-state imaging device, and electronic apparatus 株式会社钟化 2023-11-24 CN disclosed
CN-117083706-A Substrate laminate, image sensor, and method for manufacturing substrate laminate 株式会社钟化 2023-11-17 CN disclosed
US-5237042-A PROCESS FOR THE PREPARATION OF POLYBUTYLENE TEREPHTHALATE BASED POLYMER KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1993-08-17 US disclosed
US-5191121-A Sunscreen KAO CORPORATION (JP) 1993-03-02 US disclosed
US-5146002-A Sunscreen KAO CORPORATION (JP) 1992-09-08 US disclosed
EP-0416564-A2 Novel aroyl ketone derivative, UV ray absorber comprising the same, and cosmetic composition containing the same KAO CORPORATION (JP) 1991-03-13 EP disclosed
US-4584183-A SOLVENT EXTRACTION-EXCHANGE WITH METHYLISOVBUTYL METONE OR OTHER EXTRACTANTS;ENRICHMENT WESTINGHOUSE ELECTRIC CORP. (US) 1986-04-22 US disclosed