SCHEMBL3430294

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3432205	0.87	RAB9A (0.51)	ALDH1A1MAPTKMT2AMEN1NPSR1
	SCHEMBL3430712	0.86	RAB9A (0.52)	ALDH1A1MAPTKMT2AMEN1NPSR1
	SCHEMBL3760296	0.85	NPC1 (0.57)	ALDH1A1MAPTHPGDLMNANPSR1
	SCHEMBL13051112	0.85	IDH1 (0.54)	ALDH1A1MAPTKMT2AMEN1NPSR1
	SCHEMBL3406432	0.85	RAB9A (0.61)	ALDH1A1MAPTLMNAKMT2AMEN1
	SCHEMBL3429942	0.85	TSHR (0.57)	ALDH1A1MAPTKMT2AMEN1NPSR1
	SCHEMBL3428179	0.85	RAB9A (0.49)	ALDH1A1MAPTKMT2AMEN1NPSR1
	SCHEMBL3427388	0.85	RAB9A (0.49)	ALDH1A1MAPTLMNAKMT2AMEN1
	SCHEMBL3430447	0.85	KMT2A (0.54)	ALDH1A1MAPTLMNAKMT2AMEN1
	SCHEMBL3426277	0.83	RAB9A (0.57)	ALDH1A1MAPTLMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.