Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1658855 | 0.89 | TAAR1 (0.65) | TAAR1ALDH1A1HSD17B10KMT2ANPSR1 | |
| SCHEMBL1659001 | 0.85 | HPGD (0.58) | TAAR1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL1658744 | 0.80 | CA12 (0.55) | ALDH1A1KMT2AHPGDRAB9APOLB | |
| SCHEMBL1659441 | 0.77 | HPGD (0.59) | TAAR1HSD17B10HPGDPOLB | |
| SCHEMBL1660791 | 0.73 | ALDH1A1 (0.59) | ALDH1A1HPGDNPC1POLBEPHX2 | |
| SCHEMBL1660764 | 0.72 | ALDH1A1 (0.48) | ALDH1A1KMT2AHPGDMEN1NPC1 | |
| SCHEMBL1658793 | 0.71 | PTPN1 (0.58) | ALDH1A1KMT2AHPGDNPSR1MEN1 | |
| SCHEMBL4023394 | 0.71 | KMT2A (0.79) | ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL1658203 | 0.71 | LMNA (0.62) | ALDH1A1KMT2AHPGDPOLB | |
| SCHEMBL1659406 | 0.71 | SMN1; SMN2 (0.47) | TAAR1ALDH1A1KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262508-B1 | SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | BIOELECTRON TECH CORP (US) | 2018-10-03 | — | — | EP | disclosed |
| EP-2262508-A2 | SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | Edison Pharmaceuticals, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009111576-A2 | 2-SUBSTITUTED-p-QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES | EDISON PHARMACEUTICALS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |