Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 8/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | SDHA | P31040 | 2/20 | 0.37 |
| ▸ | CALML3 | P27482 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 5/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394668 | 0.82 | MAOB (0.55) | LMNAMAOBMAOAPTGS1SDHA | |
| SCHEMBL3431089 | 0.81 | MAPT (0.43) | LMNAALDH1A1MAOBMAOAPTGS1 | |
| SCHEMBL3432932 | 0.80 | MAPT (0.42) | ALDH1A1MAOBMAOA | |
| SCHEMBL3431767 | 0.80 | MAOB (0.39) | LMNAALDH1A1MAOBMAOAPTGS1 | |
| SCHEMBL3434197 | 0.79 | SMN1; SMN2 (0.42) | LMNAALDH1A1MAOBMAOAF10 | |
| SCHEMBL3432819 | 0.78 | DRD2 (0.43) | LMNAALDH1A1MAOBMAOAPTGS1 | |
| SCHEMBL14577583 | 0.76 | MAOB (0.67) | LMNAMAOBMAOAPTGS1SDHA | |
| SCHEMBL3394664 | 0.76 | MAOB (0.47) | LMNAALDH1A1MAOBMAOAPTGS1 | |
| SCHEMBL3434523 | 0.76 | F10 (0.39) | LMNAALDH1A1MAOBMAOAPTGS1 | |
| SCHEMBL3395588 | 0.76 | MAOB (0.55) | LMNAMAOBMAOAPTGS1SDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170874-A2 | NOVEL COMPOUNDS AND THEIR USE | Orchid Research Laboratories Limited (IN) | 2010-04-07 | — | — | EP | claimed |
| WO-2009001192-A2 | NOVEL COMPOUNDS AND THEIR USE | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-12-31 | — | — | WO | claimed |