Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431089 | 0.83 | MAPT (0.43) | F10MAOBMAOAMAPTHTT | |
| SCHEMBL3390798 | 0.83 | F10 (0.57) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL3434197 | 0.81 | SMN1; SMN2 (0.42) | F10MAOBMAOAMAPTHTT | |
| SCHEMBL3432249 | 0.81 | MAOB (0.41) | F10MAOBMAOAMMP2ADAMTS5 | |
| SCHEMBL3391796 | 0.78 | F10 (0.56) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL3390795 | 0.78 | MAOB (0.45) | F10MAOBMAOAMC4RGRM5 | |
| SCHEMBL3430460 | 0.76 | LMNA (0.41) | F10MAOBMAOAALDH1A1LMNA | |
| SCHEMBL3390790 | 0.76 | F10 (0.57) | F10MAOBMAOALMNAPTGS1 | |
| SCHEMBL3432932 | 0.75 | MAPT (0.42) | MAOBMAOAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3431767 | 0.75 | MAOB (0.39) | F10MAOBMAOAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170874-A2 | NOVEL COMPOUNDS AND THEIR USE | Orchid Research Laboratories Limited (IN) | 2010-04-07 | — | — | EP | claimed |
| WO-2009001192-A2 | NOVEL COMPOUNDS AND THEIR USE | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-12-31 | — | — | WO | claimed |