Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GANAB | Q14697 | 3/20 | 0.50 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | GLB1 | P16278 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | AGL | P35573 | 2/20 | 0.36 |
| ▸ | SI | P14410 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.35 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.35 |
| ▸ | GBA3 | Q9H227 | 2/20 | 0.35 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.35 |
| ▸ | MAN2B2 | Q9Y2E5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576144 | 0.89 | GANAB (0.60) | GANABGBA1GLB1MGAMGAA | |
| Pyrrolidine SCHEMBL3382491 | 0.73 | GBA1 (0.39) | GANABGBA1MGAMGAAAGL | |
| SCHEMBL7032907 | 0.72 | GBA1 (0.62) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL2265142 | 0.72 | GBA1 (0.62) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL8170837 | 0.72 | GBA1 (0.88) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL23531404 | 0.72 | GBA1 (0.62) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL8170898 | 0.72 | GBA1 (0.88) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL19328384 | 0.72 | GBA1 (0.62) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL9495785 | 0.72 | GBA1 (0.62) | GANABGBA1GLB1MGAMGAA | |
| SCHEMBL8170879 | 0.72 | GBA1 (0.88) | GANABGBA1GLB1MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015815-A2 | COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS | SUMMIT CORPORATION PLC (GB) | 2010-02-11 | — | — | WO | disclosed |