Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | PTGIR | P43119 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140820 | 0.86 | PTGDR2 (0.61) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL155869 | 0.84 | PTGDR2 (0.54) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL137368 | 0.76 | PTGDR2 (0.80) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1060090 | 0.76 | PTGDR2 (0.50) | PTGDR2TBXA2RPTGDRL3MBTL1FABP4 | |
| SCHEMBL3433653 | 0.74 | PTGDR2 (0.62) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL139650 | 0.74 | PTGDR2 (0.77) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL1058417 | 0.74 | L3MBTL1 (0.44) | PTGDR2TBXA2RPTGDRL3MBTL1FABP4 | |
| SCHEMBL137183 | 0.74 | PTGDR2 (0.75) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL141307 | 0.73 | PTGDR2 (0.68) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 | |
| SCHEMBL155416 | 0.72 | PTGDR2 (0.54) | PTGDR2TBXA2RPTGDRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257524-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2010-12-08 | — | — | EP | claimed |
| WO-2009099902-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | claimed |