Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.52 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65723 | 0.86 | ERN1 (0.56) | NFE2L2ERN1ALDH1A1KDM4ECES2 | |
| SCHEMBL764876 | 0.84 | ALDH1A1 (0.44) | NFE2L2ERN1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL29389102 | 0.84 | ALDH1A1 (0.52) | NFE2L2ALDH1A1SMN1; SMN2KDM4ECES2 | |
| SCHEMBL48607 | 0.84 | ALDH1A1 (0.52) | NFE2L2ALDH1A1SMN1; SMN2KDM4ECES2 | |
| SCHEMBL4808094 | 0.82 | ALDH1A1 (0.50) | NFE2L2ALDH1A1SMN1; SMN2KDM4ECES2 | |
| Hydrazine SCHEMBL27687525 | 0.80 | ALDH1A1 (0.48) | NFE2L2ALDH1A1SMN1; SMN2KDM4ECES2 | |
| Methylene Chloride SCHEMBL28191198 | 0.79 | ERN1 (0.48) | NFE2L2ERN1ALDH1A1SMN1; SMN2KDM4E | |
| Methylene Chloride SCHEMBL27781503 | 0.76 | ALDH1A1 (0.46) | NFE2L2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1808937 | 0.76 | ALDH1A1 (0.48) | NFE2L2ERN1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14879562 | 0.75 | ALDH1A1 (0.49) | NFE2L2ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266958-A1 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2010-12-29 | — | — | EP | disclosed |