Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389102 | 1.00 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| SCHEMBL4808094 | 0.97 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| Hydrazine SCHEMBL27687525 | 0.95 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| Methylene Chloride SCHEMBL27781503 | 0.91 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| Ethylene Glycol SCHEMBL28725409 | 0.89 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| SCHEMBL18002551 | 0.85 | NFE2L2 (0.67) | ALDH1A1SMN1; SMN2NFE2L2PTGS2RAB9A | |
| Benzidine SCHEMBL6692243 | 0.84 | KIF11 (0.45) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| Acrylic Acid SCHEMBL28129825 | 0.84 | PLA2G7 (0.42) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPTGS2 | |
| SCHEMBL3430702 | 0.84 | NFE2L2 (0.52) | ALDH1A1SMN1; SMN2NFE2L2KDM4EPLA2G7 | |
| 3-Hydroxybenzaldehyde SCHEMBL7545336 | 0.82 | CCNB2 (0.49) | ALDH1A1NFE2L2KDM4EPTGS2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2948 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4205741-B1 | CYP2E1 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY-MEDIATED DISEASES | SUZHOU LINGXI BIOTECHNOLOGY CO LTD (CN) | 2025-12-10 | — | — | EP | claimed |
| US-20250122202-A1 | EGFR INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANDONG NEW TIME PHARMACEUTICAL CO., LTD. (CN) | 2025-04-17 | — | — | US | claimed |
| EP-4403556-A1 | EGFR INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Shandong New Time Pharmaceutical Co., Ltd. (CN) | 2024-07-24 | — | — | EP | claimed |
| CN-115160300-B | Coumarin compound, preparation method thereof and application of coumarin compound in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2024-05-31 | — | — | CN | claimed |
| CN-118103371-A | EGFR inhibitor and preparation method and application thereof | 山东新时代药业有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-114409595-B | 1-Styryl isoquinoline derivative and preparation and application thereof | 南华大学附属第一医院 | 2024-05-14 | — | — | CN | claimed |
| CN-117865959-A | 2- (4-fluoro) -phenyl-6-cyclopropyl-5, 6,7, 8-tetrahydropyrido pyrimidine derivative and synthesis and application thereof | 西华大学 | 2024-04-12 | — | — | CN | claimed |
| CN-117865957-A | 2-phenyl-4-phenyl-6-N-isopropyl substituted pyrimidopyridine derivative and synthesis and application thereof | 西华大学 | 2024-04-12 | — | — | CN | claimed |
| CN-117865958-A | 4-phenyl-8 styryl substituted pyrimidopyridine benzamide compound and synthesis and application thereof | 西华大学 | 2024-04-12 | — | — | CN | claimed |
| CN-115043737-B | Tetrahydrolinalool secondary amine compound, preparation method and weeding application thereof | 中国林业科学研究院林产化学工业研究所 | 2024-03-15 | — | — | CN | claimed |
| WO-2001019808-A1 | CHEMICAL COMPOUNDS AND COMPOSITIONS AND THEIR USE AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | claimed |
| WO-2001019796-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | claimed |
| EP-0983507-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | Trega Biosciences, Inc. (US) | 2000-03-08 | — | — | EP | claimed |
| EP-0977989-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 2000-02-09 | — | — | EP | claimed |
| WO-1998034115-A1 | 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| WO-1998034111-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| EP-0653412-B1 | Process for preparing 4,5-difluorobenzaldehydes | BAYER AG (DE) | 1998-01-21 | — | — | EP | claimed |
| EP-0539274-B1 | Method for the synthesis of aldehydes and of their derivatives | RHONE POULENC CHIMIE (FR) | 1996-04-10 | — | — | EP | claimed |
| US-5489715-A | Process for preparing 4,5-difluorobenzaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-06 | — | — | US | claimed |
| US-5334769-A | By vapor phase reduction of acids, esters or anhydrides; bimetallic ruthenium-tin catalyst | RHONE-POULENC CHIMIE (FR) | 1994-08-02 | — | — | US | claimed |