SCHEMBL3430883

SCHEMBL3430883

CC(CN(C)C)c1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.69
HTR2A P28223 3/20 0.67
HRH1 P35367 3/20 0.67
TDP1 Q9NUW8 1/20 0.64
TAAR1 Q96RJ0 3/20 0.54
SLC6A2 P23975 2/20 0.52
SLC6A4 P31645 2/20 0.52
SLC6A3 Q01959 2/20 0.52
ALDH1A1 P00352 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TRPA1 O75762 2/20 0.47
RIPK1 Q13546 1/20 0.47
MAOA P21397 1/20 0.46
MAOB P27338 1/20 0.46
NISCH Q9Y2I1 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12143607 1.00 AOC3 (0.69) AOC3HTR2AHRH1TDP1TAAR1
SCHEMBL12559942 1.00 AOC3 (0.69) AOC3HTR2AHRH1TDP1TAAR1
SCHEMBL25953921 0.80 AOC3 (0.62) AOC3HTR2AHRH1TDP1TAAR1
SCHEMBL8754723 0.78 HTR2A (0.70) AOC3HTR2AHRH1TDP1SLC6A2
SCHEMBL23546236 0.77 LMNA (0.51) AOC3HTR2AHRH1SLC6A2SLC6A4
SCHEMBL21787711 0.77 AOC3 (0.48) AOC3HTR2AHRH1TDP1TAAR1
SCHEMBL19993093 0.77 AOC3 (0.48) AOC3HTR2AHRH1TDP1TAAR1
SCHEMBL22515947 0.77 HTR2A (0.69) AOC3HTR2AHRH1TDP1TAAR1
SCHEMBL3431538 0.77 AOC3 (0.59) AOC3HTR2AHRH1TDP1TAAR1
SCHEMBL8757933 0.77 ESR1 (0.55) AOC3HTR2AHRH1TDP1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3405462-B1 PROCESS FOR THE PREPARATION OF GLYCEROL CARBONATE UNIV BELFAST (GB) 2021-10-13 EP claimed
CN-109153662-B Preparation method of glycerol carbonate 英国贝尔法斯特女王大学 2021-05-14 CN claimed
US-10947211-B2 Process for the preparation of glycerol carbonate THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2021-03-16 US claimed
CN-109153662-A Preparation method of glycerol carbonate 英国贝尔法斯特女王大学 2019-01-04 CN claimed
EP-3405462-A1 PROCESS FOR THE PREPARATION OF GLYCEROL CARBONATE The Queen's University Of Belfast (GB) 2018-11-28 EP claimed
WO-2017125759-A1 PROCESS FOR THE PREPARATION OF GLYCEROL CARBONATE THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2017-07-27 WO claimed
EP-1187244-A2 Organic amines as additives for electrochemical cells MERCK PATENT GmbH (DE) 2002-03-13 EP claimed
US-6291392-B2 Catalysts containing a platinum group metal and produced in a sol-gel method, as well as a method for producing diarylcarbonates BAYER AKTIENGESELLSCHAFT (DE) 2001-09-18 US claimed
EP-3405462-B1 PROCESS FOR THE PREPARATION OF GLYCEROL CARBONATE UNIV BELFAST (GB) 2021-10-13 EP disclosed
CN-109153662-B Preparation method of glycerol carbonate 英国贝尔法斯特女王大学 2021-05-14 CN disclosed
US-10947211-B2 Process for the preparation of glycerol carbonate THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2021-03-16 US disclosed
EP-3233858-B1 ERK INHIBITORS MERCK SHARP & DOHME (US) 2019-10-30 EP disclosed
US-20190292164-A1 PROCESS FOR THE PREPARATION OF GLYCEROL CARBONATE THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2019-09-26 US disclosed
CN-109153662-A Preparation method of glycerol carbonate 英国贝尔法斯特女王大学 2019-01-04 CN disclosed
US-4217438-A Polycarbonate transesterification process GENERAL ELECTRIC COMPANY (US) 1980-08-12 US disclosed
US-4201721-A A PHENOL AND CARBON MONOXIDE WITH OXIDANT USING PLATINUM GROUP CATALYST GENERAL ELECTRIC COMPANY (US) 1980-05-06 US disclosed
US-4187242-A PHENOL, CARBON MONOXIDE, GROUP 8B ELEMENT, OXIDIZER, BASE GENERAL ELECTRIC COMPANY (US) 1980-02-05 US disclosed
US-4096169-A PHENOL, CARBON MONOXIDE, GROUP 8B CATALYST, POLYCARBONATES FROM POLYPHENOL GENERAL ELECTRIC COMPANY (US) 1978-06-20 US disclosed
US-4061617-A ANTIOXIDANT, DIELECTRIC STABILIZERS, SEMICONDUCTORS, ION EXCHANGE RESINS GENERAL ELECTRIC COMPANY (US) 1977-12-06 US disclosed
US-3959223-A Oxidation-reduction diphenoquinone-diphenonhydroquinone polymers GENERAL ELECTRIC COMPANY (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10947211-B2 Process for the preparation of glycerol carbonate GK, DGKA, DGKI AOC3 2175/4885HTR2A 4412/4885HRH1 4415/4885
US-20190292164-A1 PROCESS FOR THE PREPARATION OF GLYCEROL CARBONATE GK, DGKI, DGKA AOC3 1773/4885HTR2A 3901/4885HRH1 4186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.