Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 3/20 | 0.50 |
| ▸ | SLC16A1 | P53985 | 3/20 | 0.50 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.46 |
| ▸ | FABP3 | P05413 | 3/20 | 0.46 |
| ▸ | FABP4 | P15090 | 3/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | LIPC | P11150 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3429446 | 0.89 | SLC16A3 (0.48) | SLC16A3SLC16A1MCTS1MDM2SLC5A1 | |
| SCHEMBL3431206 | 0.88 | SLC16A3 (0.49) | SLC16A3SLC16A1MCTS1SLC5A1FABP3 | |
| SCHEMBL3431275 | 0.86 | SLC16A3 (0.48) | SLC16A3SLC16A1MCTS1SLC5A1FABP3 | |
| SCHEMBL1765293 | 0.86 | MDM2 (0.68) | SLC16A3SLC16A1MCTS1MDM2RXRA | |
| SCHEMBL3428415 | 0.85 | SLC16A3 (0.52) | SLC16A3SLC16A1MCTS1SLC5A1FABP3 | |
| SCHEMBL1110857 | 0.85 | PPP1CA (0.57) | SLC16A3SLC16A1MCTS1FABP3FABP4 | |
| SCHEMBL3430532 | 0.84 | SLC16A3 (0.62) | SLC16A3SLC16A1MCTS1PPP1CA | |
| SCHEMBL1110690 | 0.82 | SLC5A1 (0.55) | SLC16A3SLC16A1MCTS1SLC5A1PPP1CA | |
| SCHEMBL3429113 | 0.81 | HRH3 (0.54) | — | |
| SCHEMBL1764908 | 0.81 | FAAH (0.59) | SLC16A3SLC16A1MCTS1MDM2BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254885-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AiCuris GmbH & Co. KG (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009115213-A1 | (PYRAZOLYL CARBONYL)IMIDAZOLIDINONE DERIVATIVES FOR THE TREATMENT OF RETROVIRAL DISEASES | AICURIS GMBH & CO. KG (DE) | 2009-09-24 | — | — | WO | disclosed |