Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | S100B | P04271 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353952 | 1.00 | PTGS2 (0.61) | PTGS2CA12CA2CA9PTGS1 | |
| SCHEMBL3431012 | 1.00 | PTGS2 (0.61) | PTGS2CA12CA2CA9PTGS1 | |
| SCHEMBL9353955 | 1.00 | PTGS2 (0.61) | PTGS2CA12CA2CA9PTGS1 | |
| SCHEMBL8094327 | 0.87 | CA1 (0.76) | PTGS2CA12CA2CA9CA1 | |
| SCHEMBL14164182 | 0.87 | CA1 (0.76) | PTGS2CA12CA2CA9CA1 | |
| SCHEMBL11793523 | 0.87 | PTGS2 (0.52) | PTGS2CA12CA2CA9PTGS1 | |
| SCHEMBL11793519 | 0.87 | PTGS2 (0.52) | PTGS2CA12CA2CA9PTGS1 | |
| SCHEMBL9354314 | 0.84 | PTGS2 (0.69) | PTGS2CA12CA2CA9CA1 | |
| SCHEMBL11753534 | 0.84 | PTGS2 (0.69) | PTGS2CA12CA2CA9CA1 | |
| SCHEMBL9354323 | 0.84 | PTGS2 (0.69) | PTGS2CA12CA2CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786103-B2 | Method for isolating an intestinal cholesterol binding protein | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-08-31 | — | — | US | disclosed |
| US-7435727-B2 | Method for isolating an intestinal cholesterol binding protein | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-10-14 | — | — | US | disclosed |
| US-20080167451-A1 | METHOD FOR ISOLATING AN INTESTINAL CHOLESTEROL BINDING PROTEIN | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| EP-1529061-B1 | METHOD FOR ISOLATING AN INTESTINAL CHOLESTEROL BINDING PROTEIN | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-02-13 | — | — | EP | disclosed |
| EP-1529061-A1 | METHOD FOR ISOLATING AN INTESTINAL CHOLESTEROL BINDING PROTEIN | Aventis Pharma Deutschland GmbH (DE) | 2005-05-11 | — | — | EP | disclosed |
| US-20040126812-A1 | Method for isolating an intestinal cholesterol binding protein | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-07-01 | — | — | US | disclosed |
| WO-2004014947-A1 | METHOD FOR ISOLATING AN INTESTINAL CHOLESTEROL BINDING PROTEIN | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040126812-A1 | Method for isolating an intestinal cholesterol binding protein | FABP2, CETP, HDLBP | PTGS2 4016/4885CA12 3789/4885CA2 2588/4885 |
| US-20080167451-A1 | METHOD FOR ISOLATING AN INTESTINAL CHOLESTEROL BINDING PROTEIN | FABP2, CETP, HDLBP | PTGS2 4289/4885CA12 3835/4885CA2 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.