Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 18/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 17/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4361350 | 0.80 | OPRM1 (1.00) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3408765 | 0.71 | OPRM1 (1.00) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3413521 | 0.70 | OPRL1 (1.00) | OPRL1OPRM1OPRK1 | |
| SCHEMBL12521051 | 0.69 | OPRM1 (0.65) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3410758 | 0.68 | OPRL1 (0.50) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3407068 | 0.68 | OPRM1 (0.67) | OPRL1OPRM1OPRK1 | |
| SCHEMBL4349913 | 0.66 | OPRM1 (0.63) | OPRL1OPRM1OPRK1 | |
| SCHEMBL13695532 | 0.65 | OPRL1 (0.79) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3410403 | 0.65 | OPRM1 (1.00) | OPRL1OPRM1OPRK1 | |
| SCHEMBL24776648 | 0.64 | OPRM1 (0.48) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260021-A1 | SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES | Grünenthal GmbH (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009118168-A1 | SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES | Grünenthal GmbH (DE) | 2009-10-01 | — | — | WO | disclosed |