Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802158 | 0.80 | MEN1 (0.53) | MEN1KMT2AALOX12POLBGAA | |
| SCHEMBL20496869 | 0.74 | LMNA (0.54) | MEN1KMT2AALOX12POLBGAA | |
| SCHEMBL13714545 | 0.73 | POLB (0.48) | MEN1KMT2AALOX12POLBGAA | |
| SCHEMBL12049322 | 0.72 | TRPV1 (0.62) | — | |
| SCHEMBL12049555 | 0.72 | TRPV1 (0.54) | MEN1KMT2A | |
| SCHEMBL13714461 | 0.72 | HDAC3 (0.47) | MEN1KMT2AALOX12POLBGAA | |
| SCHEMBL24386417 | 0.70 | LMNA (0.42) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL24386129 | 0.70 | POLB (0.64) | MEN1KMT2APOLBGAAALDH1A1 | |
| SCHEMBL29257728 | 0.70 | SMN1; SMN2 (0.58) | MEN1KMT2AALOX12POLBGAA | |
| SCHEMBL15100298 | 0.70 | SMN1; SMN2 (0.53) | MEN1KMT2AALOX12POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428207-A1 | Alpha-2B adrenergic receptor agonist and serotonin-norepinephrine reuptake inhibitor compositions for treating chronic pain | Allergan, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |