Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13714461 | 0.91 | HDAC3 (0.47) | POLBMEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL13714516 | 0.88 | HDAC3 (0.45) | POLBMEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL7802158 | 0.75 | MEN1 (0.53) | POLBMEN1KMT2AMAPTGAA | |
| SCHEMBL343199 | 0.73 | MEN1 (0.47) | POLBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5326701 | 0.71 | HTT (0.70) | MEN1KMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL3662909 | 0.70 | SMN1; SMN2 (0.71) | MEN1KMT2ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL3207348 | 0.70 | S1PR1 (0.60) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL20496869 | 0.69 | LMNA (0.54) | POLBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL29257728 | 0.69 | SMN1; SMN2 (0.58) | POLBMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL12069261 | 0.68 | MEN1 (0.86) | POLBMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579165-B2 | Methods for derivatizing protein or peptide with sulfonic acid groups | SHIMADZU CORPORATION (JP) | 2009-08-25 | — | — | US | disclosed |