Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PER2 | O15055 | 1/20 | 0.49 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.49 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414886 | 0.83 | KDM4E (0.59) | KDM4EL3MBTL1AOC3BCAT2NPC1 | |
| SCHEMBL5188431 | 0.82 | POLB (0.47) | PER2CRY1CRY2 | |
| SCHEMBL5187871 | 0.82 | ADRB3 (0.45) | KDM4EL3MBTL1SMN1; SMN2PER2CRY1 | |
| SCHEMBL11144387 | 0.79 | ADRB3 (0.65) | KDM4EL3MBTL1LMNAADRB3ADRB2 | |
| SCHEMBL17793729 | 0.78 | GRIA4 (0.47) | PER2CRY1CRY2 | |
| SCHEMBL4985141 | 0.78 | GBA1 (0.67) | AOC3PER2CRY1CRY2 | |
| SCHEMBL28631490 | 0.77 | NPC1 (0.43) | KDM4EL3MBTL1BCAT2NPC1RAB9A | |
| Phenylpropanol SCHEMBL28034183 | 0.77 | LMNA (0.76) | KDM4EL3MBTL1AOC3BCAT2NPC1 | |
| SCHEMBL11687409 | 0.75 | LMNA (0.54) | KDM4EL3MBTL1AOC3BCAT2NPC1 | |
| SCHEMBL28111816 | 0.75 | LMNA (0.54) | KDM4EL3MBTL1AOC3BCAT2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247571-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | Uniwersytet Jagiellonski (PL) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009093916-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING AMINOALKANOLS AND THEIR USE | UNIWERSYTET JAGIELLONSKI (PL) | 2009-07-30 | — | — | WO | disclosed |
| EP-1390072-A2 | USE OF AN AMPA RECEPTOR POTENTIATOR FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF TYPE 2 DIABETES | ELI LILLY AND COMPANY (US) | 2004-02-25 | — | — | EP | disclosed |
| WO-2002089848-A2 | USE OF AN AMPA RECEPTOR POTENTIATOR FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF TYPE 2 DIABETES | ELI LILLY AND COMPANY (US) | 2002-11-14 | — | — | WO | disclosed |