SCHEMBL3432154

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3430664	0.89	RAB9A (0.56)	RAB9ATSHRUSP2NPSR1ELANE
	SCHEMBL3429942	0.86	TSHR (0.57)	RAB9ATSHRUSP2NPSR1ELANE
	SCHEMBL3430894	0.84	RAB9A (0.64)	RAB9AUSP2KMT2AALDH1A1MAPT
	SCHEMBL3427905	0.84	MAPT (0.56)	RAB9ATSHRUSP2NPSR1ELANE
	SCHEMBL3406432	0.84	RAB9A (0.61)	RAB9ATSHRUSP2NPSR1ELANE
	SCHEMBL3430604	0.83	RAB9A (0.54)	RAB9ATSHRUSP2NPSR1ELANE
	SCHEMBL3759853	0.82	NPSR1 (0.56)	RAB9ATSHRUSP2NPSR1ELANE
	SCHEMBL3427381	0.82	TSHR (0.54)	RAB9ATSHRUSP2NPSR1ELANE
	SCHEMBL3430712	0.82	RAB9A (0.52)	RAB9ATSHRUSP2NPSR1ELANE
	SCHEMBL3432147	0.82	USP2 (0.52)	RAB9ATSHRUSP2NPSR1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.