Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | BMP1 | P13497 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069712 | 0.89 | FABP5 (0.45) | RAB9ANPC1FABP5ALDH1A1LMNA | |
| SCHEMBL17500350 | 0.89 | NPC1 (0.43) | HSD17B10RAB9ANPC1FABP5POLB | |
| SCHEMBL303625 | 0.88 | NPC1 (0.42) | HSD17B10RAB9ANPC1FABP5POLB | |
| SCHEMBL4841403 | 0.88 | NPC1 (0.42) | HSD17B10RAB9ANPC1FABP5POLB | |
| SCHEMBL4784032 | 0.88 | FABP5 (0.41) | RAB9AFABP5TDP1ALDH1A1TSHR | |
| SCHEMBL208874 | 0.88 | FABP5 (0.41) | RAB9AFABP5MAPK1ALDH1A1TSHR | |
| SCHEMBL3499128 | 0.88 | HSD17B10 (0.36) | HSD17B10RAB9ANPC1FABP5POLB | |
| SCHEMBL1526171 | 0.87 | FABP5 (0.40) | RAB9AFABP5MAPK1ALDH1A1TSHR | |
| SCHEMBL5670740 | 0.87 | FABP5 (0.39) | RAB9AFABP5MAPK1ALDH1A1TSHR | |
| SCHEMBL6298094 | 0.86 | FABP5 (0.42) | HSD17B10FABP5TDP1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268050-A2 | DOSING FORM FOR A POLYMER SUPPORT, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND METHOD FOR PRODUCTION OF SAID DOSING FORM | H. Lundbeck A/S (DK) | 2003-01-02 | — | — | EP | claimed |
| WO-2001068598-A2 | DOSING FORM FOR A POLYMER SUPPORT, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND METHOD FOR PRODUCTION OF SAID DOSING FORM | H. LUNDBECK A/S (DK) | 2001-09-20 | — | — | WO | claimed |
| EP-1053001-B1 | NOVEL MIXED AMYLIN ACTIVITY COMPOUNDS | AMYLIN PHARMACEUTICALS INC (US) | 2010-12-15 | — | — | EP | disclosed |
| EP-1053001-A4 | NOVEL MIXED AMYLIN ACTIVITY COMPOUNDS | AMYLIN PHARMACEUTICALS INC (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1268050-A2 | DOSING FORM FOR A POLYMER SUPPORT, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND METHOD FOR PRODUCTION OF SAID DOSING FORM | H. Lundbeck A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068598-A2 | DOSING FORM FOR A POLYMER SUPPORT, USE OF SAID DOSING FORM IN ORGANIC CHEMICAL SYNTHESIS AND METHOD FOR PRODUCTION OF SAID DOSING FORM | H. LUNDBECK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |
| EP-1053001-A1 | NOVEL MIXED AMYLIN ACTIVITY COMPOUNDS | AMYLIN PHARMACEUTICALS, INC. (US) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040928-A1 | NOVEL MIXED AMYLIN ACTIVITY COMPOUNDS | AMYLIN PHARMACEUTICALS, INC. (US) | 1999-08-19 | — | — | WO | disclosed |