Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647763 | 0.85 | HPGD (0.42) | AKR1C3HPGDLMNAMAPK1CES2 | |
| SCHEMBL1334624 | 0.82 | AKR1C3 (0.50) | AKR1C3HPGDAPEX1LMNAMAPK1 | |
| SCHEMBL1334629 | 0.82 | AKR1C3 (0.50) | AKR1C3HPGDAPEX1LMNAMAPK1 | |
| SCHEMBL11288429 | 0.81 | NPSR1 (0.46) | AKR1C3HPGDAPEX1LMNACYP2C9 | |
| SCHEMBL11291658 | 0.81 | DHODH (0.45) | AKR1C3APEX1 | |
| SCHEMBL1336581 | 0.80 | TRPA1 (0.56) | AKR1C3HPGDAPEX1CES2CES1 | |
| SCHEMBL1336317 | 0.80 | AKR1C3 (0.48) | AKR1C3HPGDAPEX1LMNAMAPK1 | |
| SCHEMBL349596 | 0.80 | TRPA1 (0.56) | AKR1C3HPGDAPEX1CES2CES1 | |
| SCHEMBL4641824 | 0.79 | TRPA1 (0.44) | HPGDLMNAMAPK1CYP2D6TRPA1 | |
| SCHEMBL18943205 | 0.79 | TRPA1 (0.44) | HPGDLMNAMAPK1CYP2D6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399569-B2 | Reactive urethane compound having ether bond, curable composition, and cured material | SHOWA DENKO K.K. (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20100160557-A1 | REACTIVE URETHANE COMPOUND HAVING ETHER BOND, CURABLE COMPOSITION, AND CURED MATERIAL | SHOWA DENKO K.K. (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7579066-B2 | Ethylenically unsaturated group-containing isocyanate compound and process for producing the same, and reactive monomer, reactive (meth) acrylate polymer and its use | SHOWA DENKO K.K. (JP) | 2009-08-25 | — | — | US | disclosed |
| US-7232876-B2 | Phosphorus-containing urethane(meth)acrylate compounds and photosensitive compositions | SHOWA DENKO K.K. (JP) | 2007-06-19 | — | — | US | disclosed |
| US-20070083012-A1 | Curable polymer compound | SHOWA DENKO K.K. (JP) | 2007-04-12 | — | — | US | disclosed |
| US-20050107556-A1 | Phosphorus-containing urethane(meth)acrylate compounds and photosensitive compositions | SHOWA DENKO K.K. (JP) | 2005-05-19 | — | — | US | disclosed |
| EP-1468033-A1 | PHOSPHORUS-CONTAINING URETHANE (METH)ACRYLATE COMPOUNDS AND PHOTOSENSITIVE COMPOSITIONS | Showa Denko K.K. (JP) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003062296-A1 | PHOSPHORUS-CONTAINING URETHANE (METH)ACRYLATE COMPOUNDS AND PHOTOSENSITIVE COMPOSITIONS | SHOWA DENKO K. K. (JP) | 2003-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160557-A1 | REACTIVE URETHANE COMPOUND HAVING ETHER BOND, CURABLE COMPOSITION, AND CURED MATERIAL | UNC119, MLLT1, H1-0 | AKR1C3 1653/4885HPGD 1809/4885APEX1 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.