Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31190067 | 0.87 | PTGS2 (0.50) | TSHRCYP3A4CYP2D6MEN1KMT2A | |
| SCHEMBL18943205 | 0.86 | TRPA1 (0.44) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL11526523 | 0.80 | LMNA (0.41) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL13460568 | 0.80 | TRPA1 (0.44) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL29016298 | 0.80 | LMNA (0.41) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL7765727 | 0.80 | LMNA (0.42) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL11960067 | 0.79 | STAT3 (0.42) | LMNAHPGDALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL10894861 | 0.79 | HPGD (0.40) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL10894864 | 0.79 | HPGD (0.40) | TRPA1LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL3433198 | 0.79 | AKR1C3 (0.48) | TRPA1LMNAHPGDMAPK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | AUBURN UNIVERSITY (US) | 2024-07-23 | — | — | US | disclosed |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | NATIONAL SCIENCE FOUNDATION | 2022-04-21 | — | — | US | disclosed |
| EP-1797025-B1 | 4-ISOAMYLCYCLOHEXANOL AS ODIFERANT | SYMRISE GMBH & CO KG (DE) | 2008-08-13 | — | — | EP | disclosed |
| EP-1797025-A1 | 4-ISOAMYLCYCLOHEXANOL AS ODIFERANT | Symrise GmbH & Co. KG (DE) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035010-A1 | 4-ISOAMYLCYCLOHEXANOL AS ODIFERANT | SYMRISE GMBH & CO. KG (DE) | 2006-04-06 | — | — | WO | disclosed |
| EP-1021424-B1 | THIADIAZOLE AMIDE MMP INHIBITORS | UPJOHN CO (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-1021424-A1 | THIADIAZOLE AMIDE MMP INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5830869-A | METALLOPROTEASE INHIBITOR | PHARMACIA & UPJOHN COMPANY | 1998-11-03 | — | — | US | disclosed |
| WO-1997048688-A1 | THIADIAZOLE AMIDE MMP INHIBITORS | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043674-B2 | Synthetic cyclic peptides and methods of preparation and use thereof | VIP, PTMS, IAPP | TRPA1 4574/4885LMNA 1583/4885ADRA2C 4802/4885 |
| US-20220119445-A1 | SYNTHETIC CYCLIC PEPTIDES AND METHODS OF PREPARATION AND USE THEREOF | VIP, PTMS, IAPP | TRPA1 4574/4885LMNA 1583/4885ADRA2C 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.