Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807186 | 0.91 | HTR1B (0.47) | KDM4EHTR1BRAB9ACHRNB2CHRNA6 | |
| SCHEMBL19352680 | 0.90 | KDM4E (0.44) | KDM4EMAPK1CHRNB2CHRNA6CYP1A2 | |
| SCHEMBL23028310 | 0.87 | MEN1 (0.45) | KDM4EHTR1BCHRNB2CHRNA6MEN1 | |
| SCHEMBL26785579 | 0.84 | TP53 (0.54) | KDM4EHTR1BTP53MAPK1RAB9A | |
| SCHEMBL12893078 | 0.81 | CHRNB2 (0.47) | MAPK1RAB9ACHRNB2CHRNA6HPGD | |
| SCHEMBL1207888 | 0.80 | HTR1B (0.43) | KDM4EHTR1BCHRNB2CHRNA6KMT2A | |
| SCHEMBL12880467 | 0.80 | HTR1B (0.43) | KDM4EHTR1BCHRNB2CHRNA6KMT2A | |
| SCHEMBL20247449 | 0.79 | CHRNB2 (0.42) | KDM4ERAB9ACHRNB2CHRNA6SMN1; SMN2 | |
| SCHEMBL3528380 | 0.77 | KDM4E (0.55) | KDM4EHTR1BTP53MAPK1RAB9A | |
| SCHEMBL27549301 | 0.77 | KDM4E (0.55) | KDM4EHTR1BTP53MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252605-A2 | LABELLED ANALOGUES OF HALOBENZAMIDES AS MULTIMODAL RADIOPHARMACEUTICALS AND THEIR PRECURSORS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009095872-A2 | LABELLED ANALOGUES OF HALOBENZAMIDES AS MULTIMODAL RADIOPHARMACEUTICALS AND THEIR PRECURSORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2009-08-06 | — | — | WO | disclosed |