Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23028310 | 0.93 | MEN1 (0.45) | HTR1BMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3433200 | 0.91 | KDM4E (0.55) | HTR1BMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL19352680 | 0.84 | KDM4E (0.44) | CYP1A2CYP2C9CYP2C19KDM4ECHRNB2 | |
| SCHEMBL20247449 | 0.81 | CHRNB2 (0.42) | MEN1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11084194 | 0.79 | LTA4H (0.56) | HTR1BMEN1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12893078 | 0.79 | CHRNB2 (0.47) | MEN1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19952884 | 0.79 | CHRNB2 (0.40) | MEN1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12880467 | 0.78 | HTR1B (0.43) | HTR1BKMT2AKDM4ECHRNB2CHRNA6 | |
| SCHEMBL1207888 | 0.78 | HTR1B (0.43) | HTR1BKMT2AKDM4ECHRNB2CHRNA6 | |
| SCHEMBL2842190 | 0.78 | S1PR4 (0.54) | HTR1BMEN1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009033876-A1 | APTAMERS LABELED WITH 18F | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-03-19 | — | — | WO | disclosed |
| EP-2036981-A1 | Aptamers labeled with 18F | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |
| US-7456202-B2 | Marked maleimide compounds, method for preparing same and use thereof for marking macromolecules | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-11-25 | — | — | US | disclosed |
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-20050249662-A1 | Marked maleimide compounds, method for preparing same and use thereof for marking macromolecules | COMMISSARIAT A L'ENERGIE (FR) | 2005-11-10 | — | — | US | disclosed |
| EP-1517903-A2 | MARKED MALEIMIDE COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR MARKING MACROMOLECULES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004002984-A2 | MARKED MALEIMIDE COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR MARKING MACROMOLECULES | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2004-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050249662-A1 | Marked maleimide compounds, method for preparing same and use thereof for marking macromolecules | CRBN, NR2E3, NR2C2 | HTR1B 770/4885MEN1 94/4885CYP1A2 1585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.