Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 3/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376646 | 0.87 | MAPK14 (0.46) | GRIN1GRIN2BTP53BACE1MAPK14 | |
| SCHEMBL3433242 | 0.85 | MAPK14 (0.40) | MAOAMAOBTGFBR1GRIN1GRIN2B | |
| SCHEMBL3433378 | 0.82 | TGFBR1 (0.51) | TGFBR1GRIN1GRIN2BNR3C1MAPK14 | |
| SCHEMBL15147687 | 0.82 | TGFBR1 (0.46) | TGFBR1TP53NR3C1MAPTMAPK14 | |
| SCHEMBL3377364 | 0.78 | SMN1; SMN2 (0.43) | TP53 | |
| SCHEMBL3433560 | 0.78 | MAPK14 (0.46) | GRIN1GRIN2BTP53BACE1PPARG | |
| SCHEMBL3474070 | 0.75 | TGFBR1 (0.49) | TGFBR1GRIN1GRIN2BNR3C1MAPK14 | |
| SCHEMBL3475344 | 0.74 | KIT (0.48) | GRIN1GRIN2BBACE1MAPK14 | |
| SCHEMBL20777094 | 0.71 | FFAR4 (0.45) | CTSAMAOBCCKARSLC5A1GRIN1 | |
| SCHEMBL3475092 | 0.71 | ALDH1A1 (0.45) | MAOAMAOBTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | claimed |