Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | MIF | P14174 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8605013 | 0.98 | ALDH1A1 (0.53) | TYRALDH1A1ALOX15MIFLMNA | |
| Water SCHEMBL8605007 | 0.98 | ALDH1A1 (0.53) | TYRALDH1A1ALOX15MIFLMNA | |
| SCHEMBL3430867 | 0.84 | ALDH1A1 (0.50) | TYRALDH1A1ALOX15MIFLMNA | |
| SCHEMBL11859946 | 0.82 | TYR (0.40) | TYRALDH1A1ALOX15MIFLMNA | |
| SCHEMBL662595 | 0.80 | ALDH1A1 (0.55) | TYRALDH1A1ALOX15MIFLMNA | |
| SCHEMBL3718412 | 0.80 | APP (0.51) | TYRALDH1A1ALOX15MIFLMNA | |
| SCHEMBL395410 | 0.78 | ALDH1A1 (0.39) | ALDH1A1ALOX15NR1I2HSD17B10GAA | |
| SCHEMBL29818708 | 0.78 | ALDH1A1 (0.39) | TYRALDH1A1HSD17B10TRIM24TRIM33 | |
| SCHEMBL3397203 | 0.77 | MIF (0.58) | TYRALDH1A1ALOX15MIFLMNA | |
| SCHEMBL8170612 | 0.77 | MIF (0.58) | TYRALDH1A1ALOX15MIFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4587669-B2 | — | — | 2010-11-24 | — | — | JP | claimed |
| JP-2005509662-A | — | — | 2005-04-14 | — | — | JP | claimed |
| EP-1443915-A1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES | Cutanix Corporation (US) | 2004-08-11 | — | — | EP | claimed |
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | CUTANIX CORPORATION | 2003-08-21 | — | — | US | claimed |
| WO-2003043621-A1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES | CUTANIX CORPORATION (US) | 2003-05-30 | — | — | WO | claimed |
| EP-1443915-A1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES | Cutanix Corporation (US) | 2004-08-11 | — | — | EP | disclosed |
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | CUTANIX CORPORATION | 2003-08-21 | — | — | US | disclosed |
| WO-2003043621-A1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES | CUTANIX CORPORATION (US) | 2003-05-30 | — | — | WO | disclosed |
| EP-0724565-B1 | NOVEL SPIN TRAP NITRONYL HINDERED PHENOLS | OKLAHOMA MED RES FOUND (US) | 1999-08-18 | — | — | EP | disclosed |
| WO-1998010286-A1 | METHODS FOR PROCESSING CHEMICAL COMPOUNDS HAVING REACTIVE FUNCTIONAL GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 1998-03-12 | — | — | WO | disclosed |
| WO-1998001120-A1 | METHOD OF INHIBITING NADPH OXIDASE | IDUN PHARMACEUTICALS, INCORPORATED (US) | 1998-01-15 | — | — | WO | disclosed |
| WO-1996022772-A1 | METHOD FOR TREATING MULTIPLE SCLEROSIS | ELI LILLY AND COMPANY (US) | 1996-08-01 | — | — | WO | disclosed |
| EP-0251408-B1 | NOVEL ANTI-INFLAMMATORY AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR REDUCING INFLAMMATION | THE PROCTER & GAMBLE COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| US-5000961-A | Tert-butyl derivatives of benzylidenecamphor, process for preparing them, their use as antioxidant agents and cosmetic and pharmaceutical compositions containing them | L'OREAL (FR) | 1991-03-19 | — | — | US | disclosed |
| EP-0391644-A2 | Aryl-substituted rhodanine derivatives | ELI LILLY AND COMPANY (US) | 1990-10-10 | — | — | EP | disclosed |
| EP-0389176-A2 | Beta-lactams and processes for their preparation | Beecham Group p.l.c. (GB) | 1990-09-26 | — | — | EP | disclosed |
| EP-0312122-A1 | Tellurazolylidene and tellurazolium dye intermediates | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-19 | — | — | EP | disclosed |
| EP-0251408-A1 | Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation | THE PROCTER & GAMBLE COMPANY (US) | 1988-01-07 | — | — | EP | disclosed |
| EP-0167973-A1 | Redox indicators | Roche Diagnostics GmbH (DE) | 1986-01-15 | — | — | EP | disclosed |
| US-3953398-A | 3,5-DI-TERT-ALKYL-4-HYDROXYCINNAMIC ACID OR ESTER AS STABILIZER | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | TYR, HRH1, HRH2 | TYR 1/4885ALDH1A1 7/4885ALOX15 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.