Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10006748 | 0.80 | PIM1 (0.33) | ELANEPRTN3L3MBTL1 | |
| SCHEMBL28897192 | 0.76 | ELANE (0.38) | ELANEPRTN3PKMKMT2ACA1 | |
| SCHEMBL12011379 | 0.76 | HTR6 (0.45) | PKMHTR6KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1894122 | 0.76 | HTR6 (0.55) | HTR6 | |
| SCHEMBL1893107 | 0.76 | HTR6 (0.48) | HTR6KMT2ASMN1; SMN2 | |
| SCHEMBL12011373 | 0.75 | HTR6 (0.43) | HTR6KDM4EUBE2NL3MBTL1 | |
| SCHEMBL12011377 | 0.75 | HTR6 (0.43) | HTR6KDM4EUBE2NLMNAL3MBTL1 | |
| SCHEMBL1892254 | 0.75 | HTR6 (0.39) | PKMHTR6KDM4EUBE2NLMNA | |
| SCHEMBL21068128 | 0.75 | JAK2 (0.46) | ELANEPRTN3PKMHTR6CA1 | |
| SCHEMBL17518589 | 0.75 | JAK2 (0.35) | ELANEPRTN3PKMHTR6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148197-A1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-12-23 | — | — | WO | disclosed |