Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19922286 | 0.90 | KMT2A (0.39) | ELANEPRTN3KMT2ACA1CA2 | |
| SCHEMBL14487909 | 0.87 | ELANE (0.38) | ELANEPRTN3KMT2ACA1CA2 | |
| SCHEMBL16318681 | 0.85 | ALDH1A1 (0.37) | ELANEPRTN3CA1CA2CA9 | |
| SCHEMBL16207740 | 0.81 | CA1 (0.37) | ELANEPRTN3CA1CA2CA9 | |
| SCHEMBL31369076 | 0.79 | KDM4E (0.39) | ELANEPRTN3LPLLIPGCA1 | |
| SCHEMBL4441787 | 0.79 | CYP2C9 (0.41) | KMT2ACA1CA2CA9MEN1 | |
| SCHEMBL17518589 | 0.76 | JAK2 (0.35) | ELANEPRTN3KMT2ACA1CA2 | |
| SCHEMBL3433519 | 0.76 | ELANE (0.35) | ELANEPRTN3KMT2ACA1CA2 | |
| SCHEMBL17518496 | 0.76 | JAK2 (0.35) | ELANEPRTN3CA1CA2PKM | |
| SCHEMBL14857832 | 0.75 | CA1 (0.47) | ELANEPRTN3KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698011-A | PB2 inhibitor and preparation method and application thereof | 四川海思科制药有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-110637022-B | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-110637022-A | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2019-12-31 | — | — | CN | disclosed |