SCHEMBL343360

SCHEMBL343360

Oc1ccccc1CN(Cc1ccccn1)Cc1ccccn1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
LIN28A Q9H9Z2 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
APP P05067 1/20 0.46
KCNA5 P22460 1/20 0.42
KMT2A Q03164 1/20 0.41
HSPA5 P11021 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
SLC1A5 Q15758 1/20 0.40
HRH1 P35367 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16590461 1.00 MAPT (0.59) MAPTSMN1; SMN2LIN28ATDP1ALDH1A1
SCHEMBL31404243 1.00 MAPT (0.59) MAPTSMN1; SMN2LIN28ATDP1ALDH1A1
SCHEMBL31171933 0.93 MAPT (0.71) MAPTSMN1; SMN2LIN28ATDP1ALDH1A1
SCHEMBL13555815 0.91 MAPT (0.53) MAPTSMN1; SMN2LIN28ATDP1ALDH1A1
SCHEMBL15483869 0.87 MAPT (0.46) MAPTSMN1; SMN2LIN28ATDP1ALDH1A1
SCHEMBL14369562 0.86 MAPT (0.59) MAPTSMN1; SMN2LIN28ATDP1APP
SCHEMBL16154021 0.86 MAPT (0.51) MAPTSMN1; SMN2LIN28ATDP1ALDH1A1
SCHEMBL23204338 0.85 MAPT (0.47) MAPTSMN1; SMN2LIN28ATDP1ALDH1A1
SCHEMBL16099570 0.85 CYP1A2 (0.51) MAPTSMN1; SMN2LIN28ATDP1ALDH1A1
SCHEMBL15483577 0.84 MAPT (0.43) MAPTSMN1; SMN2LIN28ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5850086-A Iron complexes for bleach activation and stereospecific oxidation REGENTS OF THE UNIVERSITY OF MINNESOTA 1998-12-15 US claimed
WO-1997048710-A1 IRON COMPLEXES FOR BLEACH ACTIVATION AND STEREOSPECIFIC OXIDATION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1997-12-24 WO claimed
US-20250206704-A1 ENGINEERED IONOPHORES FOR TRANSPORT OF METAL IONS NATIONAL INSTITUTES OF HEALTH 2025-06-26 US disclosed
WO-2023183559-A1 ENGINEERED IONOPHORES FOR TRANSPORT OF METAL IONS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2023-09-28 WO disclosed
WO-2023183559-A1 ENGINEERED IONOPHORES FOR TRANSPORT OF METAL IONS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2023-09-28 WO disclosed
US-9593138-B2 Nitrile-containing enzyme inhibitors and ruthenium complexes thereof WAYNE STATE UNIVERSITY (US) 2017-03-14 US disclosed
US-9533297-B2 Ligands designed to provide highly active catalyst complexes CARNEGIE MELLON UNIVERSITY (US) 2017-01-03 US disclosed
US-20150087795-A1 LIGANDS DESIGNED TO PROVIDE HIGHLY ACTIVE CATALYST COMPLEXES CARNEGIE MELLON UNIVERSITY 2015-03-26 US disclosed
US-8338600-B2 Copper-oxygen adduct complexes, and methods of making and use JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) 2012-12-25 US disclosed
EP-2215096-B1 COPPER-OXYGEN ADDUCT COMPLEXES UNIV GIESSEN JUSTUS LIEBIG (DE) 2012-09-19 EP disclosed
US-20120016127-A1 COPPER-OXYGEN ADDUCT COMPLEXES JUSTUS-LIEBIG-UNIVERSITAET GIESSEN (DE) 2012-01-19 US disclosed
EP-2215096-A1 COPPER-OXYGEN ADDUCT COMPLEXES Justus-Liebig-Universität Gießen (DE) 2010-08-11 EP disclosed
WO-2009052809-A1 COPPER-OXYGEN ADDUCT COMPLEXES JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) 2009-04-30 WO disclosed
US-6107528-A BLEACH AND OXIDATION CATALYST IS PROVIDED COMPRISING A CATALYTICALLY ACTIVE IRON COMPLEX WHICH CAN ACTIVATE HYDROGEN PEROXIDE OR PEROXY ACIDS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2000-08-22 US disclosed
US-5850086-A Iron complexes for bleach activation and stereospecific oxidation REGENTS OF THE UNIVERSITY OF MINNESOTA 1998-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206704-A1 ENGINEERED IONOPHORES FOR TRANSPORT OF METAL IONS SLC7A1, SLC47A2, SLC39A14 MAPT 3571/4885SMN1; SMN2 4138/4885LIN28A 2497/4885
US-20120016127-A1 COPPER-OXYGEN ADDUCT COMPLEXES AOC2, AOC3, AOC1 MAPT 2441/4885SMN1; SMN2 3131/4885LIN28A 2311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.