Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2866012 | 0.95 | PDE10A (0.39) | MEN1KMT2ANPC1RAB9APDE10A | |
| SCHEMBL2855118 | 0.94 | NPC1 (0.41) | MEN1KMT2ANPC1RAB9APDE10A | |
| SCHEMBL2859516 | 0.85 | PDE10A (0.37) | MEN1KMT2ANPC1RAB9APDE10A | |
| SCHEMBL2869557 | 0.83 | GFER (0.40) | MEN1KMT2ANPC1RAB9APDE10A | |
| SCHEMBL544322 | 0.82 | NPC1 (0.41) | MEN1KMT2ANPC1RAB9APDE10A | |
| SCHEMBL2855234 | 0.81 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9APDE10A | |
| SCHEMBL2862836 | 0.81 | ALDH1A1 (0.40) | MEN1KMT2ANPC1RAB9APDE10A | |
| SCHEMBL3404966 | 0.79 | MMP2 (0.36) | ALDH1A1PPARGCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2863729 | 0.79 | NTRK1 (0.38) | MEN1KMT2ANPC1RAB9APDE10A | |
| SCHEMBL2864066 | 0.78 | SMPD1 (0.37) | MEN1KMT2ANPC1RAB9APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |