Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 3/20 | 0.46 |
| ▸ | GABRD | O14764 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142127 | 0.88 | CTSV (0.55) | TDP1ALDH1A1PARP1IMPDH2IMPDH1 | |
| SCHEMBL25800756 | 0.87 | KMT2A (0.55) | TDP1ALDH1A1PARP1IMPDH2IMPDH1 | |
| SCHEMBL6007713 | 0.87 | TDP1 (0.52) | TDP1ALDH1A1PARP1KMT2ANOS1 | |
| SCHEMBL29478497 | 0.84 | MAPT (0.57) | TDP1ALDH1A1PARP1KMT2ANOS1 | |
| SCHEMBL28907048 | 0.84 | MAPT (0.57) | TDP1ALDH1A1PARP1KMT2ANOS1 | |
| SCHEMBL11568200 | 0.81 | GRIN2D (0.56) | TDP1ALDH1A1PARP1KMT2APTPN11 | |
| SCHEMBL6829269 | 0.80 | CTSV (0.47) | TDP1PARP1IMPDH2IMPDH1KMT2A | |
| SCHEMBL16919458 | 0.80 | CTSV (0.47) | ALDH1A1PARP1IMPDH2IMPDH1KMT2A | |
| SCHEMBL30455197 | 0.79 | PARP1 (0.68) | TDP1ALDH1A1PARP1KMT2APTPN11 | |
| SCHEMBL1135541 | 0.79 | PARP1 (0.68) | TDP1ALDH1A1PARP1KMT2APTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232383-B | Method for synthesizing 4-bromocarbazole | 河南省科学院高新技术研究中心 | 2022-02-01 | — | — | CN | claimed |
| CN-109232380-B | Synthetic method of 4-bromocarbazole | 新乡市润宇新材料科技有限公司 | 2021-08-10 | — | — | CN | claimed |
| CN-109232383-A | A method of synthesis 4- bromine carbazole | 河南省科学院高新技术研究中心 | 2019-01-18 | — | — | CN | claimed |
| CN-109232380-A | A kind of synthetic method of 4- bromine carbazole | 新乡市润宇新材料科技有限公司 | 2019-01-18 | — | — | CN | claimed |
| CN-109232383-B | Method for synthesizing 4-bromocarbazole | 河南省科学院高新技术研究中心 | 2022-02-01 | — | — | CN | disclosed |
| CN-109232383-B | Method for synthesizing 4-bromocarbazole | 河南省科学院高新技术研究中心 | 2022-02-01 | — | — | CN | disclosed |
| CN-111960989-B | Preparation method of 4-bromocarbazole | 中钢集团南京新材料研究院有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-109232380-B | Synthetic method of 4-bromocarbazole | 新乡市润宇新材料科技有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-109232380-B | Synthetic method of 4-bromocarbazole | 新乡市润宇新材料科技有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-111960989-A | Preparation method of 4-bromocarbazole | 中钢集团南京新材料研究院有限公司 | 2020-11-20 | — | — | CN | disclosed |
| CN-108947890-B | Method for preparing disubstituted 4-aminocarbazole compound | 台州学院 | 2020-08-04 | — | — | CN | disclosed |
| CN-109081807-B | Method for preparing tri-substituted 4-aminocarbazole and di-substituted 1-aminodibenzo [ b, d ] thiophene compounds | 台州学院 | 2020-08-04 | — | — | CN | disclosed |
| CN-101044114-A | Nitrobenzindoles and their use in cancer therapy | AUCKLAND UNISERVICES LTD (NZ) | 2007-09-26 | — | — | CN | disclosed |
| EP-1809603-A1 | NITROBENZINDOLES AND THEIR USE IN CANCER THERAPY | Auckland Uniservices Limited (NZ) | 2007-07-25 | — | — | EP | disclosed |
| CN-1937994-A | Keratin dyeing compounds, keratin dyeing compositions containing them and their use | PROCTER & GAMBLE (US) | 2007-03-28 | — | — | CN | disclosed |
| EP-1735059-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | The Procter and Gamble Company (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20060183022-A1 | Electrochemical cell | NEC TOKIN CORORATION (JP) | 2006-08-17 | — | — | US | disclosed |
| WO-2006043839-A1 | NITROBENZINDOLES AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED (NZ) | 2006-04-27 | — | — | WO | disclosed |
| WO-2005099656-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | TDP1 3181/4885ALDH1A1 660/4885PARP1 2050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.