⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14874963 | 1.00 | — | — | |
| SCHEMBL3432957 | 0.70 | — | — | |
| SCHEMBL7238749 | 0.64 | APLNR (0.32) | — | |
| SCHEMBL7238753 | 0.64 | APLNR (0.32) | — | |
| SCHEMBL2208896 | 0.64 | APLNR (0.32) | — | |
| Hydrochloric Acid SCHEMBL4413762 | 0.63 | THRB (0.32) | — | |
| SCHEMBL5740651 | 0.63 | — | — | |
| SCHEMBL5739479 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL4093852 | 0.63 | THRB (0.32) | — | |
| SCHEMBL5739146 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946413-B2 | 3-aminocyclopentanecarboxamides as chemokine receptor agonists | PFIZER INC. (US) | 2015-02-03 | — | — | US | disclosed |
| EP-2370442-B9 | 3-Aminocyclopentanecarboxamides as chemokine receptor modulators | PFIZER (US) | 2013-09-04 | — | — | EP | disclosed |
| US-20130197008-A1 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS CHEMOKINE RECEPTOR AGONISTS | PFIZER INC. (US) | 2013-08-01 | — | — | US | disclosed |
| EP-2370442-B1 | 3-Aminocyclopentanecarboxamides as chemokine receptor modulators | PFIZER (US) | 2013-04-24 | — | — | EP | disclosed |
| US-8293903-B2 | 3-aminocyclopentanecarboxamides as chemokine receptor agonists | PFIZER INC. (US) | 2012-10-23 | — | — | US | disclosed |
| WO-2010061329-A1 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS CHEMOKINE RECEPTOR MODULATORS | PFIZER INC. (US) | 2010-06-03 | — | — | WO | disclosed |