Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13103013 | 0.98 | CHRM2 (0.33) | CHRM2CHRM1CHRM3FLT1 | |
| Trifluoromethanesulfonic Acid SCHEMBL3417344 | 0.86 | BBOX1 (0.30) | CHRM2CHRM1CHRM3 | |
| SCHEMBL16328687 | 0.80 | KDM4E (0.44) | FLT1 | |
| SCHEMBL13103034 | 0.78 | HIF1A (0.37) | CHRM2CHRM1CHRM3 | |
| Iodide SCHEMBL3417478 | 0.77 | RAB9A (0.39) | CHRM2CHRM1CHRM3 | |
| SCHEMBL3413508 | 0.76 | SLC6A4 (0.38) | — | |
| SCHEMBL9908159 | 0.76 | RAB9A (0.40) | CHRM2CHRM1CHRM3 | |
| Iodide SCHEMBL3417005 | 0.74 | GAA (0.35) | CHRM2CHRM1CHRM3 | |
| Iodide SCHEMBL3420768 | 0.74 | CHRM2 (0.41) | CHRM2CHRM1CHRM3 | |
| SCHEMBL9908170 | 0.74 | CHRM2 (0.32) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140186875-A1 | NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSIS | MONTANA STATE UNIVERSITY (US) | 2014-07-03 | — | — | US | disclosed |
| US-20100252433-A1 | NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES | NATIONAL SCIENCE FOUNDATION | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100252433-A1 | NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES | PTMS, CHAMP1, RAB5IF | CHRM1 4321/4885CHRM3 3797/4885CHRM2 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.