SCHEMBL3433937

SCHEMBL3433937

C=CCNc1ccc2c3c(cccc13)C(=O)N(CC=C)C2=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.64
ALDH1A1 P00352 2/20 0.64
RXFP1 Q9HBX9 1/20 0.64
MEN1 O00255 5/20 0.57
KMT2A Q03164 5/20 0.57
MAPK1 P28482 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
CRHBP P24387 1/20 0.57
CRHR2 Q13324 1/20 0.57
CASP3 P42574 1/20 0.51
USP2 O75604 4/20 0.51
ATM Q13315 2/20 0.51
RGS12 O14924 2/20 0.51
MAPT P10636 2/20 0.51
HTT P42858 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TLR9 Q9NR96 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
DYRK3 O43781 1/20 0.45
RPS6KB1 P23443 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29265514 0.84 ALDH1A1 (0.64) POLBALDH1A1RXFP1MEN1KMT2A
SCHEMBL18691421 0.84 KMT2A (0.74) POLBALDH1A1RXFP1MEN1KMT2A
SCHEMBL4904889 0.84 DYRK3 (0.59) POLBALDH1A1RXFP1MEN1KMT2A
SCHEMBL3754061 0.84 FGFR1 (0.58) POLBALDH1A1MEN1KMT2AMAPK1
SCHEMBL18028312 0.81 ALDH1A1 (0.61) POLBALDH1A1RXFP1MEN1KMT2A
SCHEMBL9280366 0.80 ALDH1A1 (0.58) POLBALDH1A1RXFP1MEN1KMT2A
SCHEMBL4226951 0.80 KMT2A (0.49) POLBALDH1A1RXFP1MEN1KMT2A
SCHEMBL4596137 0.78 ALDH1A1 (1.00) POLBALDH1A1RXFP1MEN1KMT2A
SCHEMBL11042478 0.78 ALDH1A1 (0.70) POLBALDH1A1RXFP1MEN1KMT2A
SCHEMBL1001022 0.78 ALDH1A1 (0.70) POLBALDH1A1RXFP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060032294-A1 Leak detection system for use in braking systems SPECTRONICS CORPORATION 2006-02-16 US claimed
US-20240224999-A1 METABOLIC INHIBITORS FOR CONTROLLING BIOFILM MC US 3 LLC (US) 2024-07-11 US disclosed
US-20240117232-A1 DROP-IN RECYCLED REFRIGERANT COMPOSITIONS HAVING NO NET GWP BEING A DROP-IN REPLACEMENT FOR R-32 AND R-454B THE COULAN COMPANY, L.L.C. (US) 2024-04-11 US disclosed
US-11746271-B1 Drop-in recycled refrigerant compositions having no net GWP The Coulan Company L.L.C. (US) 2023-09-05 US disclosed
US-20230183640-A1 METABOLIC INHIBITORS WITH EFFICACY FOR INHIBITING SULFIDE PRODUCTION IN HARSH ENVIRONMENTS LANXESS CORPORATION 2023-06-15 US disclosed
US-11655407-B1 Drop-in recycled refrigerant compositions having no net GWP replacing R-410A THE COULAN COMPANY, L.L.C. (US) 2023-05-23 US disclosed
US-20100058837-A1 DEVICE HAVING MULTIPLE LIGHT SOURCES AND METHODS OF USE THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A. 2010-03-11 US disclosed
US-7552623-B2 Enhanced leak detection dye carrier SPECTRONICS CORPORATION (US) 2009-06-30 US disclosed
US-7528144-B2 Molecules and methods for fluorescence microscopy WISYS TECHNOLOGY FOUNDATION, INC. (US) 2009-05-05 US disclosed
US-20080265213-A1 Enhanced Leak Detection Dye Carrier SPECTRONICS CORPORATION (US) 2008-10-30 US disclosed
WO-1996007088-A1 METHOD OF INTRODUCING LEAK DETECTION FLUID SPECTRONICS CORPORATION (US) 1996-03-07 WO disclosed
US-5420136-A Eradication of pathogenic biological contaminants using non-azo naphthalimide dyes MICROBIOMED CORPORATION (US) 1995-05-30 US disclosed
EP-0639080-A4 1995-03-29 EP disclosed
EP-0639080-A1 NON-AZO NAPHTHALIMIDE DYES AND USES FOR SAME MICROBIOMED CORPORATION (US) 1995-02-22 EP disclosed
WO-1994011726-A1 NON-AZO 1,8-NAPHTHALIMIDE DYES FOR THE DETECTION AND QUANTITATION OF A PARAMAGNETIC METAL CATION IN A NON-AQUEOUS MEDIUM MICROBIOMED CORPORATION (US) 1994-05-26 WO disclosed
US-5308773-A Monitoring engine wear by measuring the fluorescence of the complex formed by mixing the lubricant oil with the fluorescent dye and calibrating the concentration MICROBIOMED CORP. (US) 1994-05-03 US disclosed
US-5279967-A Using fluorophore label NALCO CHEMICAL COMPANY (US) 1994-01-18 US disclosed
US-5279967-A Using fluorophore label NALCO CHEMICAL COMPANY (US) 1994-01-18 US disclosed
WO-1993018789-A1 NON-AZO NAPHTHALIMIDE DYES AND USES FOR SAME MICROBIOMED CORPORATION (US) 1993-09-30 WO disclosed
US-5235045-A Viricides MICROBIOMED CORPORATION (US) 1993-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240224999-A1 METABOLIC INHIBITORS FOR CONTROLLING BIOFILM RIMKLA, HDHD5, SCD POLB 1222/4885ALDH1A1 1413/4885RXFP1 2993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.