Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | LIG1 | P18858 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5919579 | 0.81 | KCNA3 (0.50) | CYP3A4CYP2A6TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL30930077 | 0.81 | ALOX15 (0.43) | CYP3A4CA1CA9HPGDALDH1A1 | |
| SCHEMBL21543800 | 0.78 | TTR (0.46) | CYP2A6PTPRCHPGDMAPK1ALDH1A1 | |
| SCHEMBL9131263 | 0.78 | CA12 (0.47) | CYP3A4CYP2A6CA12CA1CA9 | |
| SCHEMBL10663882 | 0.77 | KCNA3 (0.57) | CYP3A4CYP2A6TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL17594770 | 0.77 | TOP1 (0.56) | CYP3A4CYP2A6TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL23355842 | 0.77 | MAOB (0.42) | HPGDMAPK1ALDH1A1MEN1MAPT | |
| SCHEMBL3435349 | 0.76 | CYP3A4 (0.44) | CYP3A4CYP2A6TXNRD1TXNRD3TXNRD2 | |
| SCHEMBL20454563 | 0.76 | HPGD (0.47) | CYP3A4CYP2A6CA12CA1CA9 | |
| SCHEMBL21543827 | 0.75 | CYP2A6 (0.48) | CYP2A6HPGDHSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361218-B2 | Coloring composition, method for production thereof, and coloring method | Dainischiseika Color & Chemicals Mfg. Co., Ltd. (JP) | 2013-01-29 | — | — | US | disclosed |
| US-20100291359-A1 | Coloring composition, method for production thereof, and coloring method | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2010-11-18 | — | — | US | disclosed |
| EP-2206751-A1 | COLORING COMPOSITION, METHOD FOR PRODUCTION THEREOF, AND COLORING METHOD | Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) | 2010-07-14 | — | — | EP | disclosed |
| US-4310527-A | DISORDERS OF CAROIAC RHYTHM AND CORONARY HEART DISEASES AND HYDPERTENSION | CIBA-GEIGY CORPORATION (US) | 1982-01-12 | — | — | US | disclosed |
| US-4261898-A | ADHESION PROMOTERS, CURING AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |
| US-4176124-A | ADHESION PROMOTERS BETWEEN SOLIDS AND ORGANIC RESINS OR CURING AGENTS FOR EPOXIDE RESINS | CIBA-GEIGY CORPORATION (US) | 1979-11-27 | — | — | US | disclosed |
| EP-0003758-A1 | Etherified hydroxy-benzodiheterocycles and their acid addition salts, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-09-05 | — | — | EP | disclosed |
| US-4140789-A | ADRENERGIC BLOCKING AGENTS, CARDIOTONIC, ANTIARRHYTHMIA, HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |