SCHEMBL3434458

SCHEMBL3434458

CCCCCNc1nc(NCCCCC)nc(-c2ccc(OC)cc2)n1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CHRNA7 P36544 4/20 0.58
▸ KCNH3 Q9ULD8 2/20 0.49
▸ ALDH1A1 P00352 2/20 0.46
▸ HPGD P15428 1/20 0.46
▸ CASP3 P42574 1/20 0.45
▸ SENP8 Q96LD8 1/20 0.45
▸ SENP7 Q9BQF6 1/20 0.45
▸ SENP6 Q9GZR1 1/20 0.45
▸ POLB P06746 2/20 0.44
▸ RAD52 P43351 1/20 0.44
▸ RXFP1 Q9HBX9 1/20 0.44
▸ GAA P10253 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ GBA1 P04062 1/20 0.42
▸ ADORA3 P0DMS8 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ TLR8 Q9NR97 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8039439 0.80 KCNH3 (0.65) KCNH3ALDH1A1POLBGBA1KMT2A
SCHEMBL28827857 0.77 CASP3 (0.51) CHRNA7CASP3SENP8SENP7SENP6
SCHEMBL1594282 0.77 CNR2 (0.52) ALDH1A1HPGDCASP3SENP7POLB
SCHEMBL7537505 0.76 POLB (0.65) KCNH3ALDH1A1POLBGBA1TLR8
SCHEMBL514975 0.75 KCNH3 (0.63) KCNH3ALDH1A1KMT2A
SCHEMBL30149861 0.74 CHRNA7 (1.00) CHRNA7KCNH3ALDH1A1GAAL3MBTL1
SCHEMBL11331749 0.74 GAA (0.70) ALDH1A1GAAL3MBTL1KMT2A
SCHEMBL3298621 0.73 KMT2A (0.67) KCNH3KMT2A
SCHEMBL3299537 0.73 KMT2A (0.67) KCNH3KMT2A
SCHEMBL14441528 0.73 KMT2A (0.67) KCNH3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187575-B2 Triazine derivatives as UV absorbers BASF SE Ludwigshafen (DE) 2012-05-29 — — US disclosed
EP-1585493-B1 TRIAZINE DERIVATIVES AS UV ABSORBERS BASF SE (DE) 2010-09-01 — — EP disclosed
US-20060153783-A1 Triazine derivatives as uv absorbers BASF SE (DE) 2006-07-13 — — US disclosed
EP-1585493-A1 TRIAZINE DERIVATIVES AS UV ABSORBERS Ciba SC Holding AG (CH) 2005-10-19 — — EP disclosed
WO-2004064797-A1 TRIAZINE DERIVATIVES AS UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING, INC. (CH) 2004-08-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060153783-A1 Triazine derivatives as uv absorbers C1R, C1S, CBR3 CHRNA7 611/4885KCNH3 1461/4885ALDH1A1 1577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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