Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355739 | 0.76 | USP2 (0.42) | USP2TP53ALDH1A1MEN1POLB | |
| SCHEMBL1847760 | 0.70 | USP2 (0.70) | USP2TP53ALDH1A1MEN1POLB | |
| SCHEMBL3434512 | 0.69 | USP2 (0.45) | USP2TP53ALDH1A1MEN1POLB | |
| SCHEMBL2355747 | 0.69 | USP2 (0.43) | USP2TP53ALDH1A1MEN1POLB | |
| SCHEMBL4748426 | 0.65 | USP2 (0.62) | USP2TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL2215939 | 0.65 | USP2 (0.46) | USP2TP53ALDH1A1MEN1POLB | |
| SCHEMBL571063 | 0.63 | USP2 (0.69) | USP2TP53ALDH1A1POLBKMT2A | |
| SCHEMBL7798234 | 0.62 | SMN1; SMN2 (0.57) | USP2TP53ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4779632 | 0.62 | SMN1; SMN2 (0.62) | USP2TP53ALDH1A1MEN1KMT2A | |
| SCHEMBL457954 | 0.61 | NPC1 (0.73) | USP2TP53ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035219-A2 | PYRAZOLO PYRIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2010-04-01 | — | — | WO | disclosed |