Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 2/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397038 | 0.89 | KCNH2 (0.42) | KCNH2OXTREGLN2EGLN1SLC22A12 | |
| SCHEMBL3396132 | 0.89 | KCNH2 (0.41) | KCNH2OXTREGLN2CYP11B1CYP11B2 | |
| SCHEMBL3396008 | 0.89 | TNIK (0.43) | KCNH2TNIKEGLN2EGLN1DRD1 | |
| SCHEMBL3392062 | 0.86 | KCNH2 (0.54) | KCNH2EGLN2TGFBR1 | |
| SCHEMBL3427227 | 0.84 | KCNH2 (0.42) | KCNH2TNIKEGLN2DRD1CYP11B1 | |
| SCHEMBL3432960 | 0.84 | KCNH2 (0.43) | KCNH2TNIKEGLN2DRD1CYP11B1 | |
| SCHEMBL3394274 | 0.83 | KCNH2 (0.43) | KCNH2EGLN2 | |
| Hydrochloric Acid SCHEMBL3432843 | 0.83 | KCNH2 (0.42) | KCNH2TNIKEGLN2DRD1CYP11B1 | |
| SCHEMBL3398420 | 0.82 | KCNH2 (0.42) | KCNH2OXTREGLN2DRD1CYP11B1 | |
| SCHEMBL3434686 | 0.81 | KCNH2 (0.44) | KCNH2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |