Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393341 | 0.90 | KCNH2 (0.43) | KCNH2TGFBR1METAP2METAP1GRM5 | |
| SCHEMBL3397575 | 0.87 | KCNH2 (0.43) | KCNH2TGFBR1EGLN2 | |
| SCHEMBL3432960 | 0.86 | KCNH2 (0.43) | KCNH2EGLN2LRRK2MAPK14 | |
| SCHEMBL3434735 | 0.86 | KCNH2 (0.40) | KCNH2TGFBR1EGLN2 | |
| SCHEMBL3397038 | 0.86 | KCNH2 (0.42) | KCNH2TGFBR1GRM5EGLN2 | |
| SCHEMBL3396132 | 0.86 | KCNH2 (0.41) | KCNH2GRM5EGLN2 | |
| SCHEMBL3398420 | 0.86 | KCNH2 (0.42) | KCNH2EGLN2LRRK2 | |
| SCHEMBL3394274 | 0.86 | KCNH2 (0.43) | KCNH2EGLN2 | |
| Hydrochloric Acid SCHEMBL3432843 | 0.85 | KCNH2 (0.42) | KCNH2EGLN2LRRK2MAPK14 | |
| SCHEMBL3392275 | 0.85 | KCNH2 (0.46) | KCNH2TGFBR1METAP2METAP1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |