Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.38 |
| ▸ | RELA | Q04206 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396008 | 0.87 | TNIK (0.43) | KCNH2EGLN2S1PR1 | |
| SCHEMBL3427227 | 0.86 | KCNH2 (0.42) | KCNH2EGLN2 | |
| SCHEMBL3392062 | 0.86 | KCNH2 (0.54) | KCNH2EGLN2 | |
| SCHEMBL3432960 | 0.85 | KCNH2 (0.43) | KCNH2EGLN2 | |
| SCHEMBL3395956 | 0.85 | MAPT (0.41) | KCNH2RAB9ASMN1; SMN2MAPTHPGD | |
| Hydrochloric Acid SCHEMBL3432843 | 0.84 | KCNH2 (0.42) | KCNH2EGLN2 | |
| SCHEMBL3434735 | 0.83 | KCNH2 (0.40) | KCNH2EGLN2 | |
| SCHEMBL3434686 | 0.83 | KCNH2 (0.44) | KCNH2ALOX15MAPK1 | |
| SCHEMBL3426389 | 0.83 | KCNH2 (0.43) | KCNH2ALOX15RAB9AMEN1KMT2A | |
| SCHEMBL3397167 | 0.82 | KCNH2 (0.42) | KCNH2MEN1KMT2AEGLN2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |