Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3436055 | 0.90 | DRD4 (0.41) | OPRL1OGFRL1CYP2C19ALDH1A1DRD4 | |
| SCHEMBL3436631 | 0.85 | PROKR1 (0.47) | OPRL1OGFRL1DRD4 | |
| SCHEMBL3436049 | 0.84 | CYP2C19 (0.44) | KMT2AMEN1CYP2C19ALDH1A1DRD4 | |
| Hydrochloric Acid SCHEMBL2078695 | 0.83 | CYP2C19 (0.43) | KMT2AMEN1CYP2C19ALDH1A1DRD4 | |
| SCHEMBL28853811 | 0.77 | PTPN11 (0.43) | KMT2AMEN1PTPN11DRD3 | |
| SCHEMBL3436380 | 0.76 | DRD4 (0.52) | OPRL1ALDH1A1DRD4 | |
| SCHEMBL3436624 | 0.76 | DRD4 (0.55) | OPRL1DRD4 | |
| SCHEMBL9671400 | 0.74 | RBP4 (0.48) | CYP2C19 | |
| SCHEMBL4356330 | 0.74 | CYP3A4 (0.45) | PTPN11DRD2DRD1DRD4DRD5 | |
| SCHEMBL24652524 | 0.72 | ALDH1A1 (0.57) | KMT2AALDH1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163746-B2 | Azolecarboxamide derivative | ASTELLAS PHARMA INC. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | OPRL1 51/4885OGFRL1 367/4885KMT2A 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.