SCHEMBL3435138

SCHEMBL3435138

COC(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.58
SLC6A5 Q9Y345 1/20 0.49
GSR P00390 1/20 0.46
RNPEP Q9H4A4 1/20 0.44
CPB2 Q96IY4 10/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CPB1 P15086 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9698704 1.00 FOLH1 (0.58) FOLH1SLC6A5GSRRNPEPCPB2
Hydrochloric Acid SCHEMBL31741284 0.98 FOLH1 (0.57) FOLH1SLC6A5GSRRNPEPCPB2
SCHEMBL9716637 0.95 FOLH1 (0.51) FOLH1SLC6A5GSRCPB2CA1
SCHEMBL9716631 0.95 FOLH1 (0.51) FOLH1SLC6A5GSRCPB2CA1
SCHEMBL9716635 0.95 FOLH1 (0.51) FOLH1SLC6A5GSRCPB2CA1
SCHEMBL28456990 0.87 FOLH1 (0.60) FOLH1SLC6A5GSRRNPEPCPB2
SCHEMBL2628236 0.87 GABRR1 (0.43) FOLH1SLC6A5
SCHEMBL15148580 0.86 ERAP2 (0.43) FOLH1SLC6A5GSRCPB2
SCHEMBL9716676 0.85 FOLH1 (0.54) FOLH1SLC6A5GSRRNPEPCPB2
SCHEMBL9716669 0.85 FOLH1 (0.54) FOLH1SLC6A5GSRRNPEPCPB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561710-A Ionizable lipid JK-0044, preparation method and use in self-replicating mRNA delivery system 宁波君健生物科技有限公司 2024-08-30 CN claimed
CN-111808278-B Branched antibacterial polyamino acid and preparation method and application thereof 中山大学 2021-12-21 CN claimed
CN-111808278-A Branched antibacterial polyamino acid and preparation method and application thereof 中山大学 2020-10-23 CN claimed
CN-122005830-A Temperature-sensitive hydrogel containing doxorubicin-loaded dendrimer as well as preparation method and application thereof 南通大学 2026-05-12 CN disclosed
CN-121758312-A Method for preparing di (lauramide glutamine) lysine and method for preparing sodium di (lauramide glutamine) lysine 深圳市迈思立生物科技有限公司 2026-03-31 CN disclosed
CN-118561710-A Ionizable lipid JK-0044, preparation method and use in self-replicating mRNA delivery system 宁波君健生物科技有限公司 2024-08-30 CN disclosed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed
CN-116057070-A anti-CD 40 binding molecules and bispecific antibodies comprising same 礼进生物医药科技(上海)有限公司 2023-05-02 CN disclosed
CN-109134778-B Charge inversion type polymer micelle, drug-loaded micelle and preparation method thereof 西南民族大学 2021-03-09 CN disclosed
EP-1581559-B1 VL DAb FC FUSION DOMANTIS LTD (GB) 2010-06-30 EP disclosed
EP-0178911-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1992-01-22 EP disclosed
US-5079167-A Enzymatic resolution of amino acid carbamate racemates GESELLSCHAFT FUR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) (DE) 1992-01-07 US disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0243606-A1 Process for enzymatic racemate cleavage Gesellschaft für Biotechnologische Forschung mbH (GBF) (DE) 1987-11-04 EP disclosed
WO-1987005329-A1 PROCESS FOR THE SEPARATION OF RACEMATES GESELLSCHAFT FÜR BIOTECHNOLOGISCHE FORSCHUNG MBH ( (DE) 1987-09-11 WO disclosed
EP-0178911-A2 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1986-04-23 EP disclosed