SCHEMBL9716631

SCHEMBL9716631

COC(=O)NC(CCCN)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 5/20 0.51
SLC6A5 Q9Y345 1/20 0.43
CPB2 Q96IY4 6/20 0.40
GNPAT O15228 2/20 0.40
NOD1 Q9Y239 2/20 0.39
GSR P00390 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TGFBR1 P36897 1/20 0.38
CPB1 P15086 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716637 1.00 FOLH1 (0.51) FOLH1SLC6A5CPB2GNPATNOD1
SCHEMBL9716635 1.00 FOLH1 (0.51) FOLH1SLC6A5CPB2GNPATNOD1
SCHEMBL9698704 0.95 FOLH1 (0.58) FOLH1SLC6A5CPB2GSRCA1
SCHEMBL3435138 0.95 FOLH1 (0.58) FOLH1SLC6A5CPB2GSRCA1
Hydrochloric Acid SCHEMBL31741284 0.93 FOLH1 (0.57) FOLH1SLC6A5CPB2GSRCA1
SCHEMBL2628236 0.89 GABRR1 (0.43) FOLH1SLC6A5TGFBR1
SCHEMBL27966321 0.85 FOLH1 (0.40) FOLH1GNPATNOD1TGFBR1
SCHEMBL9716665 0.84 FOLH1 (0.47) FOLH1SLC6A5CPB2NOD1
SCHEMBL9716671 0.84 FOLH1 (0.47) FOLH1SLC6A5CPB2NOD1
SCHEMBL9716663 0.84 FOLH1 (0.47) FOLH1SLC6A5CPB2NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090099061-A1 SYNTHESIS OF CAROTENOID ANALOGS OR DERIVATIVES WITH IMPROVED ANTIOXIDANT CHARACTERISTICS CARDAX PHARMACEUTICALS, INC. 2009-04-16 US disclosed
EP-0178911-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1992-01-22 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0178911-A2 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1986-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099061-A1 SYNTHESIS OF CAROTENOID ANALOGS OR DERIVATIVES WITH IMPROVED ANTIOXIDANT CHARACTERISTICS CAT, HBZ, POLL FOLH1 3749/4885SLC6A5 4647/4885CPB2 907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.